ID   A3CQZ0_STRSV            Unreviewed;       731 AA.
AC   A3CQZ0;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   SubName: Full=Ribonucleotide reductase, class III, anaerobic, putative {ECO:0000313|EMBL:ABN45595.1};
DE            EC=1.17.4.2 {ECO:0000313|EMBL:ABN45595.1};
GN   Name=nrdD {ECO:0000313|EMBL:ABN45595.1};
GN   OrderedLocusNames=SSA_2230 {ECO:0000313|EMBL:ABN45595.1};
OS   Streptococcus sanguinis (strain SK36).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=388919 {ECO:0000313|EMBL:ABN45595.1, ECO:0000313|Proteomes:UP000002148};
RN   [1] {ECO:0000313|EMBL:ABN45595.1, ECO:0000313|Proteomes:UP000002148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK36 {ECO:0000313|EMBL:ABN45595.1,
RC   ECO:0000313|Proteomes:UP000002148};
RX   PubMed=17277061; DOI=10.1128/JB.01808-06;
RA   Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P.,
RA   Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D.,
RA   Paik S., Peterson D.L., Macrina F.L., Buck G.A.;
RT   "Genome of the opportunistic pathogen Streptococcus sanguinis.";
RL   J. Bacteriol. 189:3166-3175(2007).
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DR   EMBL; CP000387; ABN45595.1; -; Genomic_DNA.
DR   RefSeq; WP_011837630.1; NC_009009.1.
DR   RefSeq; YP_001036145.1; NC_009009.1.
DR   AlphaFoldDB; A3CQZ0; -.
DR   STRING; 388919.SSA_2230; -.
DR   KEGG; ssa:SSA_2230; -.
DR   PATRIC; fig|388919.9.peg.2115; -.
DR   eggNOG; COG1327; Bacteria.
DR   eggNOG; COG1328; Bacteria.
DR   HOGENOM; CLU_002707_2_0_9; -.
DR   OrthoDB; 9804622at2; -.
DR   Proteomes; UP000002148; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01675; RNR_III; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW   ProRule:PRU00493}; Oxidoreductase {ECO:0000313|EMBL:ABN45595.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002148}.
FT   DOMAIN          14..108
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
FT   DOMAIN          597..723
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000259|PROSITE:PS51149"
FT   MOD_RES         696
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ   SEQUENCE   731 AA;  83386 MW;  725AF1AD10D3E6C9 CRC64;
     MILREEKFET APAIYVEKRD GRRVTFDVSK IYKAMVRAAQ EVGPLNPMLE AKLEAITDRI
     VAEISSRFAK YVKIYEIQNI VEHELLNAKE YAIAENYITY RTQRDFERSK ATDINFTIDK
     LLNKDRTVVN ENANKDSDVF NTQRDLTAGI VGKSIGLKML PPHVANAHQK GDIHYHDLDY
     SPYTPMTNCC LIDFDGMLKN GFKIGNAEVE SPKSIQTATA QISQIIANVA SSQYGGCSAD
     RIDEVLAPYA ELNYQKHLKD AEQWVLPDKR EEYAWAKTKK DIYDAMQSLE YEINTLFTSN
     GQTPFTSLGF GLGTNRFERE IQKAILNIRI KGLGSEHRTA IFPKLIFTLK RGLNLEPGTP
     NYDIKELALE CATKRMYPDV LSYDKIIDLT GSFKVPMGCR SFLQGWKDEN GQEVNSGRMN
     LGVVTVNLPR IALESEGDLD KFWELFNERM NIAEDALVYR VERTKEASPA NAPILYQYGA
     FGQRLGKYDQ VDQLFTHRRA TVSLGYIGLY EVAAVFYGGN WETNPEAKDF TVAIVKDMKR
     RVEEWSEQYD YHFSVYSTPS ESLTDRFCRL DTEKFGVVPD ITDKEYYTNS FHYDVRKNPT
     PFEKLDFEKI YPEVGASGGF IHYCEYPVLQ QNPKALEAVW DYAYDRVGYL GTNTPIDRCY
     KCNFEGDFTP TERGFTCPNC GNSDPKTVDV VKRTCGYLGN PQARPMVNGR HKEISARVKH
     MNGSTIKYEG N
//