ID A3CR45_STRSV Unreviewed; 112 AA.
AC A3CR45;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Cadmium efflux system transcriptional regulator (ArsR-like), putative {ECO:0000313|EMBL:ABN45650.1};
GN Name=cadX {ECO:0000313|EMBL:ABN45650.1};
GN OrderedLocusNames=SSA_2289 {ECO:0000313|EMBL:ABN45650.1};
OS Streptococcus sanguinis (strain SK36).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=388919 {ECO:0000313|EMBL:ABN45650.1, ECO:0000313|Proteomes:UP000002148};
RN [1] {ECO:0000313|EMBL:ABN45650.1, ECO:0000313|Proteomes:UP000002148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK36 {ECO:0000313|EMBL:ABN45650.1,
RC ECO:0000313|Proteomes:UP000002148};
RX PubMed=17277061; DOI=10.1128/JB.01808-06;
RA Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P.,
RA Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D.,
RA Paik S., Peterson D.L., Macrina F.L., Buck G.A.;
RT "Genome of the opportunistic pathogen Streptococcus sanguinis.";
RL J. Bacteriol. 189:3166-3175(2007).
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DR EMBL; CP000387; ABN45650.1; -; Genomic_DNA.
DR RefSeq; WP_000711078.1; NC_009009.1.
DR RefSeq; YP_001036200.1; NC_009009.1.
DR AlphaFoldDB; A3CR45; -.
DR STRING; 388919.SSA_2289; -.
DR GeneID; 83690540; -.
DR KEGG; ssa:SSA_2289; -.
DR PATRIC; fig|388919.9.peg.2173; -.
DR eggNOG; COG0640; Bacteria.
DR HOGENOM; CLU_097806_7_3_9; -.
DR OrthoDB; 9794330at2; -.
DR Proteomes; UP000002148; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR018334; ArsR_HTH.
DR InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; NF033788; HTH_metalloreg; 1.
DR PANTHER; PTHR43132; ARSENICAL RESISTANCE OPERON REPRESSOR ARSR-RELATED; 1.
DR PANTHER; PTHR43132:SF6; TRANSCRIPTIONAL REPRESSOR SMTB HOMOLOG; 1.
DR Pfam; PF01022; HTH_5; 1.
DR PRINTS; PR00778; HTHARSR.
DR SMART; SM00418; HTH_ARSR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00846; HTH_ARSR_1; 1.
DR PROSITE; PS50987; HTH_ARSR_2; 1.
PE 4: Predicted;
KW Cadmium resistance {ECO:0000256|ARBA:ARBA00043263};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002148}.
FT DOMAIN 24..112
FT /note="HTH arsR-type"
FT /evidence="ECO:0000259|PROSITE:PS50987"
SQ SEQUENCE 112 AA; 13044 MW; A17E965D75A31817 CRC64;
MKKDSICQVD VINQQNVTTA TNYLEKEKVQ KSLRILSKFT DNKQINIIFY LLAVEELCVC
DIACLLNLSM ASASHHLRKL ANQNILDTRR EGKIIYYFIK DEEIRDFFNQ LG
//
