ID A3CWP9_METMJ Unreviewed; 821 AA.
AC A3CWP9;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Heavy metal translocating P-type ATPase {ECO:0000313|EMBL:ABN57799.1};
GN OrderedLocusNames=Memar_1873 {ECO:0000313|EMBL:ABN57799.1};
OS Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=368407 {ECO:0000313|EMBL:ABN57799.1, ECO:0000313|Proteomes:UP000002146};
RN [1] {ECO:0000313|EMBL:ABN57799.1, ECO:0000313|Proteomes:UP000002146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35101 / DSM 1498 / JR1
RC {ECO:0000313|Proteomes:UP000002146};
RX PubMed=21304656; DOI=10.4056/sigs.32535;
RA Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT type strain JR1.";
RL Stand. Genomic Sci. 1:189-196(2009).
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DR EMBL; CP000562; ABN57799.1; -; Genomic_DNA.
DR RefSeq; WP_011844708.1; NC_009051.1.
DR AlphaFoldDB; A3CWP9; -.
DR STRING; 368407.Memar_1873; -.
DR GeneID; 76729949; -.
DR KEGG; mem:Memar_1873; -.
DR eggNOG; arCOG01576; Archaea.
DR eggNOG; arCOG02763; Archaea.
DR HOGENOM; CLU_001771_0_3_2; -.
DR OrthoDB; 8588at2157; -.
DR Proteomes; UP000002146; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 2.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 2.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006122; HMA_Cu_ion-bd.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR NCBIfam; TIGR00003; copper ion binding protein; 1.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 2.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 2.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 2.
DR PROSITE; PS50846; HMA_2; 2.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Copper transport {ECO:0000256|ARBA:ARBA00022796};
KW Ion transport {ECO:0000256|ARBA:ARBA00022796};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022796}.
FT DOMAIN 6..72
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 74..140
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 821 AA; 86872 MW; 85FEF4B959E418F2 CRC64;
MPEEKRKAEL KISGMHCASC ALNVERALQG RDNVYDARVN FANETATVEY DPAKTTLADL
ERTVSDAGYE VVRSEATVRI GGMVCASCAR VIEASLADLD GVYEARVNLA NENARVVYNP
EFVTTAEIRA AVEDAGYQYL GLEEEIPEDV EARMREADLR DKFRRFAVGF AVSIPLFFYM
LFGMPGAAAL PVSINLVMLV VTLPVFLYVS APIFRAAAAA LRNRALTMDV MYAMGIGVAY
GASLLGTFQI VLTADFNFYE TAVMLAAFLT LGRYLEARAK GRTSEAIKKL VGLRPRTATV
IRDGREVEVP VEAVAVGDVI LVRPGEKVPV DGTVVGGESS VNEAMITGEP IPADKKEGDE
VVGGTLNVNG VLRIRAEKIG KDMVLSQIIR LVRDAQGSKP PVERIADVAV SYFIPAVLAI
ATAAFLVWYV GAGASLLFSL TVLISVLVVA CPCALGLATP TAVTVGIGRG AELGLLIRNG
EALEVSEKLT AIVFDKTGTL TRGKPDVTDV VALAVPEDRL LAVAAAVEHN SQHPLAAAVV
RRAESAGVTV PASERFTTFG GRGVSAVVDG EEVLIGNQPF LEEHGVTVPE GAERRIAALQ
DEGKTAVLVA AGADLAGILA IADTLKPTTK RAVAELKRMG LSVTMITGDN ERTANAIARE
VGIEDVHAGV LPQEKAQEVR ALQSRGEVVA FVGDGINDAP ALAQADVGIA IGSGTDVAIE
SGDIVLIRDD LIDAVAAVEL SRKVMSRIKQ NLFWAFAYNS ALIPLAAGVL YPFFGITFRP
ELAALAMALS SVTVVSLSLL LKTYIPPAKR GTLSEADARG S
//
