ID A3CY00_METMJ Unreviewed; 707 AA.
AC A3CY00;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=acetate--CoA ligase (ADP-forming) {ECO:0000256|ARBA:ARBA00012957};
DE EC=6.2.1.13 {ECO:0000256|ARBA:ARBA00012957};
GN OrderedLocusNames=Memar_2327 {ECO:0000313|EMBL:ABN58250.1};
OS Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=368407 {ECO:0000313|EMBL:ABN58250.1, ECO:0000313|Proteomes:UP000002146};
RN [1] {ECO:0000313|EMBL:ABN58250.1, ECO:0000313|Proteomes:UP000002146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35101 / DSM 1498 / JR1
RC {ECO:0000313|Proteomes:UP000002146};
RX PubMed=21304656; DOI=10.4056/sigs.32535;
RA Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT type strain JR1.";
RL Stand. Genomic Sci. 1:189-196(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetate + ATP + CoA = acetyl-CoA + ADP + phosphate;
CC Xref=Rhea:RHEA:15081, ChEBI:CHEBI:30089, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288,
CC ChEBI:CHEBI:456216; EC=6.2.1.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001619};
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DR EMBL; CP000562; ABN58250.1; -; Genomic_DNA.
DR AlphaFoldDB; A3CY00; -.
DR STRING; 368407.Memar_2327; -.
DR KEGG; mem:Memar_2327; -.
DR eggNOG; arCOG01338; Archaea.
DR eggNOG; arCOG01340; Archaea.
DR HOGENOM; CLU_007415_2_2_2; -.
DR Proteomes; UP000002146; Chromosome.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT DOMAIN 37..73
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 707 AA; 75811 MW; 039D1865763A0E03 CRC64;
MGGPTNPCNR APVMPGRIGL PRGIPMPERM LTESEGYRLL ESCGIPVPPN HLATSAEDAR
AAAGRIGYPV VMKVISPQIV HKSDVGGVIT GIESPDGAEE AFGTIMQNAA ARAPEATVAG
IIVEKQMPAG LEVLIGGKTD PSFGKVITFG LGGKLVELLE DVSIRVLPVT DSEIRAMIRE
IEGYRLIRGY RGESPKDEEA LVRVIAAMAQ AFIEDPRIRE FDLNPVIVYE KGVSVVDARI
IVGDTAGGAP ARLRVRAPPD LFYPASIAVI GASASPNKVG YSVLRNLLSF PGNLYPVNPS
RTELFGRKTY PSVTGIPDPV DWAVVAVPAR IVPEVMEECG KKGIRLAVIV TAGFREIGGE
GTVLEEKVTA IARRHGIRII GPNCLGIMMP HMGINATFDP VSPRPGDVAF ISQSGAIITT
VVDWSLPEEF GFSTVISVGN QADLGFEHFL RFAEQDEKTR SVTLYVEEIQ DGRGFMQIVG
EVAKRKPVVA VKSGSSRKGR AAASSHTGSL AGSYDVYVAA FRQAGVIVAR SLRDAFNLAE
LLASEGYPKG KRAIAVTSAG GFAVLASDYA ETYGVDMVDL PDDVLRELNA FLPPFWNHAN
PMDILGDADA TRFAALFDVL IRHQNFWDIV FVIAVPTTLV DPAHVANEIV RLSRNTEKMV
VGCMLGGDSI RSGLRILRGS RIPNFEELED AFKAVGSILE VGAVRQE
//
