ID A3F963_CHICK Unreviewed; 355 AA.
AC A3F963;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Muscleblind like splicing regulator 2 {ECO:0000313|Ensembl:ENSGALP00010007079.1};
DE SubName: Full=Muscleblind-like 2 isoform 4 {ECO:0000313|EMBL:ABN43468.1};
GN Name=MBNL2 {ECO:0000313|EMBL:ABN43468.1,
GN ECO:0000313|Ensembl:ENSGALP00010007079.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|EMBL:ABN43468.1};
RN [1] {ECO:0000313|EMBL:ABN43468.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Retina {ECO:0000313|EMBL:ABN43468.1};
RX PubMed=18095352; DOI=10.1002/dvdy.21408;
RA Huang H., Wahlin K.J., McNally M., Irving N.D., Adler R.;
RT "Developmental regulation of muscleblind-like (MBNL) gene expression in the
RT chicken embryo retina.";
RL Dev. Dyn. 237:286-296(2008).
RN [2] {ECO:0000313|Ensembl:ENSGALP00010007079.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010007079.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the muscleblind family.
CC {ECO:0000256|ARBA:ARBA00038226}.
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DR EMBL; EF363025; ABN43468.1; -; mRNA.
DR RefSeq; NP_001156845.1; NM_001163373.1.
DR RefSeq; XP_015129926.1; XM_015274440.1.
DR Ensembl; ENSGALT00010012515.1; ENSGALP00010007079.1; ENSGALG00010005272.1.
DR GeneID; 418784; -.
DR CTD; 10150; -.
DR VEuPathDB; HostDB:geneid_418784; -.
DR GeneTree; ENSGT00950000182897; -.
DR HOGENOM; CLU_053536_0_0_1; -.
DR Proteomes; UP000000539; Chromosome 1.
DR Bgee; ENSGALG00000016890; Expressed in muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1370.210; -; 2.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR12675; MUSCLEBLIND-LIKE PROTEIN; 1.
DR PANTHER; PTHR12675:SF4; MUSCLEBLIND-LIKE PROTEIN 2; 1.
DR Pfam; PF00642; zf-CCCH; 2.
DR Pfam; PF14608; zf-CCCH_2; 2.
DR SMART; SM00356; ZnF_C3H1; 4.
DR PROSITE; PS50103; ZF_C3H1; 4.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 13..41
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 47..73
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 176..204
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 212..238
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 13..41
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 47..73
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 176..204
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 212..238
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
SQ SEQUENCE 355 AA; 38253 MW; 9CBF57F91EC8AAFA CRC64;
MALNVAPVRD TKWLTLEVCR QFQRGTCSRS DEECKFAHPP KSCQVENGRV IACFDSLKGR
CTRENCKYLH PPTHLKTQLE INGRNNLIQQ KTAAAMLAQQ MQFMFPGTPL QPVPTFPVGP
TIGTNTAISF APYLTPVTPG VGLVPTEILP TPPVIVPGSP PVSVPGSTAT QKLLRTDKLE
VCREFQRGNC ARGETDCRFA HPADSTMIDT NDNTVTVCMD YIKGRCMREK CKYFHPPAHL
QAKIKAAQHQ ANQAAVAAQA AAAAATVMAF PPGVLHPLPK RQALEKSNGA SAVFNPSVLH
YQQALANAQL QQHAAFIPTV PMMHNATAAT VSAATTPATS VPFAATATAN QIILK
//
