GenomeNet

Database: UniProt
Entry: A3F9C4_PIG
LinkDB: A3F9C4_PIG
Original site: A3F9C4_PIG 
ID   A3F9C4_PIG              Unreviewed;       255 AA.
AC   A3F9C4; I3LUT6;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   23-MAY-2018, entry version 37.
DE   SubName: Full=Mucosal addressin cell adhesion molecule-1 isoform b {ECO:0000313|EMBL:ABN13861.1};
GN   Name=MADCAM1 {ECO:0000313|EMBL:ABN13861.1,
GN   ECO:0000313|Ensembl:ENSSSCP00000027887};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|EMBL:ABN13861.1};
RN   [1] {ECO:0000313|EMBL:ABN13861.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Mesenteric lymph node {ECO:0000313|EMBL:ABN13861.1};
RX   PubMed=18533264; DOI=10.1016/j.molimm.2008.04.017;
RA   Bourges D., Meurens F., Berri M., Chevaleyre C., Zanello G.,
RA   Levast B., Melo S., Gerdts V., Salmon H.;
RT   "New insights into the dual recruitment of IgA+ B cells in the
RT   developing mammary gland.";
RL   Mol. Immunol. 45:3354-3362(2008).
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000027887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000027887};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Proteomes:UP000008227};
RA   Zha H.-G.;
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Ensembl:ENSSSCP00000027887}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
RN   [5] {ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Proteomes:UP000008227};
RG   International Swine Genome Sequencing Consortium;
RA   Warr A., Hall R., Kim K., Koren S., Phillippy A.M., Bickhart D.M.,
RA   Rosen B., Schroeder S., Hume D.A., Talbot R., Chow W., Howe K.,
RA   Nonneman D.J., Rohrer G.A., Watson M., Smith T.P., Archibald A.L.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Proteomes:UP000008227};
RA   Warr A., Hall R., Kim K., Koren S., Phillippy A.M., Bickhart D.M.,
RA   Rosen B., Schroeder S., Hume D.A., Talbot R., Chow W., Howe K.,
RA   Nonneman D.J., Rohrer G.A., Watson M., Smith T.P., Archibald A.L.;
RT   "Exploiting long read sequencing technologies to establish high
RT   quality highly contiguous pig reference genome assemblies.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AEMK02000012; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EF363128; ABN13861.1; -; mRNA.
DR   UniGene; Ssc.18928; -.
DR   ProteinModelPortal; A3F9C4; -.
DR   Ensembl; ENSSSCT00000023867; ENSSSCP00000027887; ENSSSCG00000039500.
DR   eggNOG; ENOG410J133; Eukaryota.
DR   eggNOG; ENOG411140D; LUCA.
DR   GeneTree; ENSGT00510000049549; -.
DR   HOVERGEN; HBG108114; -.
DR   Reactome; R-SSC-198933; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
DR   Reactome; R-SSC-216083; Integrin cell surface interactions.
DR   Proteomes; UP000008227; Chromosome 2.
DR   Bgee; ENSSSCG00000021190; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098640; F:integrin binding involved in cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:2000403; P:positive regulation of lymphocyte migration; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR015169; Adhes-Ig-like.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR037413; MADCAM1.
DR   PANTHER; PTHR14162; PTHR14162; 2.
DR   Pfam; PF09085; Adhes-Ig_like; 1.
DR   ProDom; PD336606; Adhes-Ig-like; 1.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008227};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    255       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014565608.
FT   TRANSMEM    226    248       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      112    219       Adhes-Ig_like. {ECO:0000259|Pfam:
FT                                PF09085}.
SQ   SEQUENCE   255 AA;  27605 MW;  16B37273827A2983 CRC64;
     MEQGLALLLP LFLGLLQPGH GGRLEVEPPE PEVAVAVGES RQFACRLACA DGQVASVQWR
     GLDTSLGSVK SGTGSSVLWV HNASLSAAGT RMCVGYCGKR SFHHTVNLLV FAFPDQLTVS
     PESLVPGRDR EVACTAHNVS PARPDVFSMS LLLGDQELEG VQTLDRDVME EPQEDEDPLF
     QVTERWLLPP LGIPAPPTLH CQVTMSLPGL NRSHRQSIPG SLPASAALWT GSLVLGLLLL
     VFLIYRLWKR CRPTS
//
DBGET integrated database retrieval system