ID   A3JZD7_9RHOB            Unreviewed;       477 AA.
AC   A3JZD7;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:EBA09840.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:EBA09840.1};
GN   ORFNames=SSE37_08528 {ECO:0000313|EMBL:EBA09840.1};
OS   Sagittula stellata E-37.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Sagittula.
OX   NCBI_TaxID=388399 {ECO:0000313|EMBL:EBA09840.1, ECO:0000313|Proteomes:UP000005713};
RN   [1] {ECO:0000313|EMBL:EBA09840.1, ECO:0000313|Proteomes:UP000005713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E-37 {ECO:0000313|EMBL:EBA09840.1,
RC   ECO:0000313|Proteomes:UP000005713};
RA   Moran M.A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EBA09840.1}.
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DR   EMBL; AAYA01000002; EBA09840.1; -; Genomic_DNA.
DR   RefSeq; WP_005856103.1; NZ_AAYA01000002.1.
DR   AlphaFoldDB; A3JZD7; -.
DR   eggNOG; COG0824; Bacteria.
DR   eggNOG; COG1250; Bacteria.
DR   OrthoDB; 9803287at2; -.
DR   Proteomes; UP000005713; Unassembled WGS sequence.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   CDD; cd00586; 4HBT; 1.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF13279; 4HBT_2; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:EBA09840.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005713}.
FT   DOMAIN          7..170
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          180..247
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   477 AA;  51167 MW;  C3A23583D76E10B6 CRC64;
     MTPTTKKAAI IGGGVIGGGW AARFLLNGWD VAVFDPDPEA ERKIGAVLDR ARASLPALYD
     RALPPEGALT FCDSLVDALQ GADWVQESVS ERLELKHKVY DQIAAHLPEG GFIASSTSGF
     KASDLAANGA PVVVVHPFNP VYLLPLAEIT GEPELRAKAL PVVQSIGMSP LEMHAEIDAF
     IGNRFQEAIW REALWMIKDG IATTAQIDDA MRMGFGLRLA QMGLFETYRL AGGEAGMASY
     MEQFGPSLHW PWSRLTDVPD LDAALVQAIS DQSDAQSGHM TIARMETLRD DNLVAILRGL
     RRTGSGAGGV ITAHEESLDS DGEIDGLPVT QRRAVPVTWT DYNGHMNEAA YLELGTWATD
     GLMKLVGADD AYVASGKSFF TVDTRIRYLG EVHRGAVLTV TTQVLEGAGK KMKLFHRILK
     EDGSLAATIE TLMLHTDLNT RRACLPEPAV AEALETLAAA HAGRDAPGAG GSVGQRN
//