ID A3LNR7_PICST Unreviewed; 487 AA.
AC A3LNR7;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=DNA polymerase delta small subunit (Hydroxyurea sensitive protein HYS2) {ECO:0000313|EMBL:ABN64373.2};
DE EC=2.7.7.7 {ECO:0000313|EMBL:ABN64373.2};
GN Name=HYS2 {ECO:0000313|EMBL:ABN64373.2};
GN ORFNames=PICST_40682 {ECO:0000313|EMBL:ABN64373.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN64373.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN64373.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SIMILARITY: Belongs to the DNA polymerase delta/II small subunit
CC family. {ECO:0000256|ARBA:ARBA00006035}.
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DR EMBL; CP000496; ABN64373.2; -; Genomic_DNA.
DR RefSeq; XP_001382402.2; XM_001382365.1.
DR AlphaFoldDB; A3LNR7; -.
DR STRING; 322104.A3LNR7; -.
DR GeneID; 4837670; -.
DR KEGG; pic:PICST_40682; -.
DR eggNOG; KOG2732; Eukaryota.
DR HOGENOM; CLU_021763_2_0_1; -.
DR InParanoid; A3LNR7; -.
DR OMA; HCILIGT; -.
DR OrthoDB; 1604at2759; -.
DR Proteomes; UP000002258; Chromosome 2.
DR GO; GO:0043625; C:delta DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.430; -; 1.
DR Gene3D; 3.60.21.50; -; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR040663; DNA_pol_D_N.
DR InterPro; IPR024826; DNA_pol_delta/II_ssu.
DR PANTHER; PTHR10416; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR PANTHER; PTHR10416:SF0; DNA POLYMERASE DELTA SUBUNIT 2; 1.
DR Pfam; PF18018; DNA_pol_D_N; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ABN64373.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transferase {ECO:0000313|EMBL:ABN64373.2}.
FT DOMAIN 47..188
FT /note="DNA polymerase delta subunit OB-fold"
FT /evidence="ECO:0000259|Pfam:PF18018"
FT DOMAIN 210..438
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
SQ SEQUENCE 487 AA; 54845 MW; E081277A78C4B72F CRC64;
MVEFTDYFNR EVTPSTEYTR TSFKDSSDYP KQEEFIISAK DRKYDRQYFS MYQYRFKNLK
ERIIGNAIQK WGDGTKRVNG QTIVKQDKIL DITSGKLCWV VGTVFCDLKD KLNIFQDVEK
GIDDVLPLVP DSYVGDDENS MTTMLEDESG RAILHNEEFL SKNILVTGCI VGVLGIEISA
GIFEIMDIVY PEASPQKPLT LKASEGKGKV AIVSGLNLEE GVDADLKLEL LKQYVTGSLG
SSEDSKTASS VCRLIIAGDS VKPIKEMSDR SNRDFVTTNN YGSKNISQYN PESLVKFDEF
LREILVSLPV SVMPGNNDMG EICLPQQPLH KSLFHSNARY LNGEYLERLT NPYWFNFGEL
RVLGTSGQNV HDILKYLSKN TTAAPELILK IMESHIKWQN FIPTAPDTLY CYPFDNSDPF
TLVDETPHVY FVGNQQQYAS EVYTYASTTT GNSGSVRLVS VPRFSETGEL VLLDLDTLET
EVVQISL
//
