ID A3LS31_PICST Unreviewed; 533 AA.
AC A3LS31;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Purine-cytosine transport protein {ECO:0000313|EMBL:ABN65839.2};
GN ORFNames=PICST_30904 {ECO:0000313|EMBL:ABN65839.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN65839.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN65839.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; CP000497; ABN65839.2; -; Genomic_DNA.
DR RefSeq; XP_001383868.2; XM_001383831.1.
DR AlphaFoldDB; A3LS31; -.
DR GeneID; 4838259; -.
DR KEGG; pic:PICST_30904; -.
DR eggNOG; ENOG502QR29; Eukaryota.
DR HOGENOM; CLU_026016_2_1_1; -.
DR InParanoid; A3LS31; -.
DR OMA; GRYFMGY; -.
DR OrthoDB; 65220at2759; -.
DR Proteomes; UP000002258; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF8; VITAMIN B6 TRANSPORTER TPN1; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 69..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 533 AA; 59310 MW; F604E3E9A56AA769 CRC64;
MDIESKKEKF VISRDFENGS EDSASFAPPK YISWIYKLDN FGIETRGIER VSTEERRSLA
ANKSSLNRFL HVFGLWIAAC GGLTTMSSFF LPTLLFGLSM KDSLICGLIS MNLGCLVPAY
CSTMGPKSGC RQMVGARFLF GQWGVKFVSL ICIVGGIGWS VVNCVLGGQI LIAINNNIPL
SVGIVIIGVI SLVIAIFGIR VLLNFQTILS IPLIIASILF YVVVLKKVDY VHESNVLVAE
QGFSGLTVRG NWLSFFAIGY SVTATWGSGA SDYYILFPEE TPSYQIFIVT FLGIAVPSTF
VAIIGTICGS IAYAYQPWND AYNNFGIGGL INECFKPWGR FGSFIVVLLY ISLICNNIMN
TYSVAFEFQL IDRKLAYIPR WCWAIVMTII YVVLSVAGKE HFSTILSNFL PMLGYWISMY
ITILLEENIF FRSSIKTKTL HHNEFDEKAN SDWSYNWSNW NKPKGITMGL AADLSFAIGV
VGAVLGMNQV YFQGPIAKKI GDYSGDVGMW LCGGFTGVVY PFLRYWELKR FGR
//
