ID A3LSR8_PICST Unreviewed; 685 AA.
AC A3LSR8;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=PICST_59466 {ECO:0000313|EMBL:ABN66282.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN66282.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN66282.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
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DR EMBL; CP000498; ABN66282.2; -; Genomic_DNA.
DR RefSeq; XP_001384311.2; XM_001384274.1.
DR AlphaFoldDB; A3LSR8; -.
DR STRING; 322104.A3LSR8; -.
DR GeneID; 4838593; -.
DR KEGG; pic:PICST_59466; -.
DR eggNOG; KOG1842; Eukaryota.
DR HOGENOM; CLU_026440_1_0_1; -.
DR InParanoid; A3LSR8; -.
DR OMA; QASNFLH; -.
DR OrthoDB; 1441111at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd15761; FYVE1_Vac1p_like; 1.
DR CDD; cd15737; FYVE2_Vac1p_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR006642; Rad18_UBZ4.
DR InterPro; IPR021565; Rbsn_Rab-bd.
DR InterPro; IPR036531; Rbsn_Rab-bd_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR39490; ARRESTIN DOMAIN-CONTAINING PROTEIN D; 1.
DR PANTHER; PTHR39490:SF12; FYVE ZINC FINGER FAMILY PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF11464; Rbsn; 1.
DR SMART; SM00064; FYVE; 2.
DR SMART; SM00734; ZnF_Rad18; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF140125; Rabenosyn-5 Rab-binding domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 382..470
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 112..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78988 MW; 48FB763DC8EB3BED CRC64;
MANQHSRPTQ RRNLGSPFKS PEAIAKMSKS QNSNMTTSST LQTPDNVKSV QYEASPTPVR
HTAVKSLAPS SQYEEVPVAD PTKQTDSLTC PICSEHMLTL SQLNQHIDDA HQEKEMETDS
SNAANNLSNG GTSVGRLLGT NDVKRWFSGK SENQRKTPQK RKTISLDMLD DERGFSFSDN
GDGFRESPVS SRVTSPLPNS GNSPYSKHKR ITRTHWKHPS TTPLCSIRDC GKTLNVKNGI
VNCRKCGLLF CNEHTQYRVK LKNSEDVEKE PPVYNSTFEG TWSKCCCDCY YSKPDLAVGT
QVNSRDLTSQ FAKKRQELLD DKQLARVKVQ KRFIKLADLL AETSFHERNE SKTLWGAIQK
TLIDSKSEAE KEIIGYDNWQ SDKEATNCTI CFVRFNIVIR RHHCRLCGNI VCDDPYGARK
SCSIVVPLSK LLEKLHNLNY SRLVKDNLKT LLHEDSIKFR CCVDCKNSLL YDWKLLHLRT
PKQNETEIFL IYNAILAQKH QISQLLPKYA KHIDTTSDEE ESYTNRLRIK IMTFLKDFEN
LTTQFRGRFF ISENNKLLVI DDFAADSRLI TNIYQSSIMF LQDNLIWYKQ LNDKHKEIEQ
QRLKQSLEER AKEETPEVPR LTKKQIRELR EQLMVMNEQK FLVENMIMES TKARRFEELS
SLEQNKRELD MTIENLETEL GEFGF
//
