ID A3LSU5_PICST Unreviewed; 847 AA.
AC A3LSU5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Glutamated carboxypeptidase {ECO:0000313|EMBL:ABN65956.2};
DE EC=3.4.17.21 {ECO:0000313|EMBL:ABN65956.2};
GN Name=GCP1 {ECO:0000313|EMBL:ABN65956.2};
GN ORFNames=PICST_72031 {ECO:0000313|EMBL:ABN65956.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN65956.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN65956.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; CP000498; ABN65956.2; -; Genomic_DNA.
DR RefSeq; XP_001383985.2; XM_001383948.1.
DR AlphaFoldDB; A3LSU5; -.
DR STRING; 322104.A3LSU5; -.
DR GeneID; 4838629; -.
DR KEGG; pic:PICST_72031; -.
DR eggNOG; KOG2195; Eukaryota.
DR HOGENOM; CLU_005688_1_1_1; -.
DR InParanoid; A3LSU5; -.
DR OMA; RIIDPIY; -.
DR OrthoDB; 67337at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR CDD; cd03874; M28_PMSA_TfR_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR PANTHER; PTHR10404:SF72; ZINC METALLOPROTEASE TRE2-RELATED; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:ABN65956.2};
KW Hydrolase {ECO:0000313|EMBL:ABN65956.2};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:ABN65956.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 123..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 450..579
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 715..844
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 96030 MW; 353B673E61E79806 CRC64;
MASHMRYTPL TADPSHTLPS FPPSYDDLDD NNDDYTYSSS ATPAIEQFEL DDGIDGIDDG
ITRRTQREGL LVRASLMTKK FANNFNNSII HPVSQIIDPI YEGYKYFQQK YEQNILKLGN
PLVVKRLLYV LFIMIVIFFV TKHNVNDGVN GTSGGTFSAG KFYNIDKLSS SVDDFISAKL
MKENLEYFSS MSHITGSNGD LTLARYIETY MHNNGIRIMD MNQLQSYTNY PVYNEKDTYL
KLSDNSFSAH LYEMNNKTME HLAYNPNALN TNGPVESHFI YGNYGTQEDY QKLISSGIDL
TDAILLIKYG GSIPEPNKVS FGQQSKVKAI VFITPKFEFG TGDSKQEFVD VIQKANVGLT
RVDPGDVLTP GWSSEDGYVT RLPWFRSSTT PKIPTIPISW EDGEKLLSKL EGSGVKFDDG
YFSGKGKSSS VPTMVLKIAN EERATHQIWN VVGSIQGREQ NEKGIIIGSS RDSTCYGTIS
SNTGTVVMLE MIKVFTSLQR KYNWSPSRSI YFVSFDATEY NLAGSAEWIE NRKDSLRKEG
YAYIDLSDAI SGDDLSIKAS PFVEDVIKKA LKQVETDVTK NDNGNEKLSL YDLYLRQQGN
DGISNDLIES KNYIPFINLV NMPSLELKFS GKKYPKNSCY DNFENFEKSA IDPDMNKHRE
LVKVLSLIAL RLAESPMIPF DFQKLASKLT HYVDDLEKYS RDIISTLEQE NKPVLHFKSL
RDSIEILRNA ANSLQSWGDS WKQYVENSAE IEPSMLAMNR WKRNENMVAF NQKFLVRNHM
KDTRPGFANV LFGVPFMAPE VSDGKYEWNT FPRIRDSLYL HDFNAAQDQI NKLASLVQEA
CQELDSQ
//
