ID A3LUI5_PICST Unreviewed; 583 AA.
AC A3LUI5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=Transcriptional regulator of multiple amino acid permeases {ECO:0000313|EMBL:ABN66243.2};
DE Flags: Fragment;
GN Name=SSY1.5 {ECO:0000313|EMBL:ABN66243.2};
GN ORFNames=PICST_58499 {ECO:0000313|EMBL:ABN66243.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN66243.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN66243.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. YAT (TC 2.A.3.10) family. {ECO:0000256|ARBA:ARBA00006983}.
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DR EMBL; CP000498; ABN66243.2; -; Genomic_DNA.
DR RefSeq; XP_001384272.2; XM_001384235.1.
DR AlphaFoldDB; A3LUI5; -.
DR STRING; 322104.A3LUI5; -.
DR GeneID; 4838907; -.
DR KEGG; pic:PICST_58499; -.
DR eggNOG; KOG1286; Eukaryota.
DR HOGENOM; CLU_007946_8_6_1; -.
DR InParanoid; A3LUI5; -.
DR OMA; FIRFYYG; -.
DR OrthoDB; 2048918at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF39; SPS-SENSOR COMPONENT SSY1; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..542
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABN66243.2"
SQ SEQUENCE 583 AA; 64218 MW; 3D28D27D510A896C CRC64;
HGKTLQRKLK VRHLQMISFG GTLGVGLFLN SGKAFTIAGG LGTLLAFAIC GTIVLATIVS
FCEMVTFVSV VDGVSGLSSR FVDDAFGFCV GWLYFFSFAF GLAGEVVASV IMLAYYPSLN
IPESKGNSAG FVTLFLGLVV LCNLVDIRVF GEIEYISSLI KLVWVLAMIV IMIVMNRGGF
DNGVIGFKFW QHDRSDFANN LIFGLFRPTF NLHDNGSSSE SAGIGSDKGR FLSLVVALMI
VSYAYSGTEI VCIAACEAQN PRKALPSATK RVFWRILIFY CLSAFAVSLN IYAGDPRLLR
YYSGSTGVSA NEFSTNYAIK YVGGVNCISD SVVYAGVGSG AQSPWIVALQ SAALCRFSNV
VNGFLVFFAV SCGNAQLYVS SRTVYSLALQ KKAPKQLTYC NRFGIPYVAV LFAASFGLLS
YICVSERATV VFMNLTSIIA SSGIFVWFAM SLSFIRFYYG LRRRPDIISR DDKNYPYRSP
FQPYSAFVGL IGSAFIILGM GFVVFLQDEW DTMFFFSSYG TLIVFAVLYV GYRLVRGTRI
PTLDTLDFDS GRTELDRVIW DRGREYDAGN FKDLTQKWMS FLA
//
