ID A3LWW3_PICST Unreviewed; 387 AA.
AC A3LWW3;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Mitochondrial tricarboxylate/dicarboxylate carrier protein {ECO:0000313|EMBL:ABN67703.2};
GN Name=YFL5 {ECO:0000313|EMBL:ABN67703.2};
GN ORFNames=PICST_62279 {ECO:0000313|EMBL:ABN67703.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN67703.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN67703.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; CP000500; ABN67703.2; -; Genomic_DNA.
DR RefSeq; XP_001385732.2; XM_001385695.1.
DR AlphaFoldDB; A3LWW3; -.
DR STRING; 322104.A3LWW3; -.
DR GeneID; 4840325; -.
DR KEGG; pic:PICST_62279; -.
DR eggNOG; KOG0756; Eukaryota.
DR HOGENOM; CLU_015166_5_1_1; -.
DR InParanoid; A3LWW3; -.
DR OMA; TRMQSKY; -.
DR OrthoDB; 2342190at2759; -.
DR Proteomes; UP000002258; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR049563; TXTP-like.
DR PANTHER; PTHR45788:SF5; AFR253WP; 1.
DR PANTHER; PTHR45788; SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 2.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|RuleBase:RU000488}.
FT REPEAT 10..92
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 288..375
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 387 AA; 42732 MW; 66A2247AA5BF71E7 CRC64;
MATTSPQSGD SLLTALISGC TAAAVSGTLT YPLDFIKTQQ QLNNHAYMNK WNIPGNYPGS
IAQLYRGCSA LVIGSVIKNA TRLISYNWSS KFMAIDTYDS QGNSKTKTSP PRIVIAGAMS
AFIETLWLIP FENIKIVMIQ NQTLQNEITR SEKAKIPFDI TGGRIKHHHQ RRLSPGNLFT
KQYISPHAYF SSELLAQYNG KHHSKFSHSA SHNKLDALIS KYNKNPTLTY LGTIKEMYQM
KGVGAFTAGT FITFTRQMAI SWVWLSTYNA TRQLIDPHNS EQSWFGHKHT AIQSIGLHVL
SSIAVIGFTQ PLDVIKSHIQ SKNGKAIYKD SLSTAYRLFV EQGPRSLFKG ALPRGLKVLV
SGGLTAAIYS YVEDIVNVAG GQTVFAS
//
