ID A3MZ04_ACTP2 Unreviewed; 246 AA.
AC A3MZ04;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=Spermidine/putrescine transport system permease protein PotC {ECO:0000256|ARBA:ARBA00039580};
GN Name=potC {ECO:0000313|EMBL:ABN73390.1};
GN OrderedLocusNames=APL_0282 {ECO:0000313|EMBL:ABN73390.1};
OS Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=416269 {ECO:0000313|EMBL:ABN73390.1, ECO:0000313|Proteomes:UP000001432};
RN [1] {ECO:0000313|EMBL:ABN73390.1, ECO:0000313|Proteomes:UP000001432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L20 {ECO:0000313|EMBL:ABN73390.1,
RC ECO:0000313|Proteomes:UP000001432};
RX PubMed=18065534; DOI=10.1128/JB.01845-07;
RA Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA Nash J.H.;
RT "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT (serotype 5b).";
RL J. Bacteriol. 190:1495-1496(2008).
CC -!- FUNCTION: Required for the activity of the bacterial periplasmic
CC transport system of putrescine and spermidine.
CC {ECO:0000256|ARBA:ARBA00037216}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Cell membrane
CC {ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000256|ARBA:ARBA00007069}.
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DR EMBL; CP000569; ABN73390.1; -; Genomic_DNA.
DR AlphaFoldDB; A3MZ04; -.
DR STRING; 416269.APL_0282; -.
DR EnsemblBacteria; ABN73390; ABN73390; APL_0282.
DR KEGG; apl:APL_0282; -.
DR eggNOG; COG1177; Bacteria.
DR HOGENOM; CLU_016047_3_0_6; -.
DR Proteomes; UP000001432; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR43848; PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTI; 1.
DR PANTHER; PTHR43848:SF5; SPERMIDINE_PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTC; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000001432};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 88..112
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 118..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 162..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 220..242
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 50..238
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 246 AA; 27334 MW; 6C56807BB21775F7 CRC64;
MFVVFAYLYI PIIILVVNSF NEDRYGLQWK GFSWNWYERL FANDTLVQAT MNSLTIAFFA
ATFSTVLGAL TSIALYRYKF RGMQMVGGLL FIVMMSPDIV MAVSLLVLFM ILGVRLGFIS
LLIAHITFCL PYVVITISSR LSDFDGKMLE AAKDLGASEV TILRKIILPL ALPSIISGWL
LSFTISLDDV VVSSFVTSPS YEVLPLKIFS LVKTGVTPEV NALATIMIIF SLTLVVLSQL
VVRKKA
//
