ID A3QJE2_SHELP Unreviewed; 830 AA.
AC A3QJE2;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ABO25590.1};
DE Flags: Precursor;
GN OrderedLocusNames=Shew_3724 {ECO:0000313|EMBL:ABO25590.1};
OS Shewanella loihica (strain ATCC BAA-1088 / PV-4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=323850 {ECO:0000313|EMBL:ABO25590.1, ECO:0000313|Proteomes:UP000001558};
RN [1] {ECO:0000313|EMBL:ABO25590.1, ECO:0000313|Proteomes:UP000001558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1088 / PV-4 {ECO:0000313|Proteomes:UP000001558};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G.,
RA Fredrickson J., Tiedje J., Richardson P.;
RT "Complete sequence of Shewanella loihica PV-4.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000606; ABO25590.1; -; Genomic_DNA.
DR AlphaFoldDB; A3QJE2; -.
DR STRING; 323850.Shew_3724; -.
DR KEGG; slo:Shew_3724; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_6; -.
DR OrthoDB; 1316910at2; -.
DR Proteomes; UP000001558; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001558};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 263..335
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 421..560
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 569..822
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 830 AA; 94059 MW; 869F72E53DF75024 CRC64;
MLKFFSRPSL ILFAPLVCVL LFAFFITSSY FVERQQRRDY VSASQVEHLS QGLMRMNHLV
AMAAKAQDFT RVEEELALLG SDIRLSVYTL IDRRGNIRFA NHGVWRDSSA QLVIDGYESQ
AHENSVAEGR SRIYFNDKRQ SIQAYYPITP QLSSLSVERP ELIYLEYDMA PMLAASDETV
LVGLMRTGAI ALATTLVLLG LFYYFVLSPI RYLSRQAAAL GQRETDSRQK PIESPFIELH
SLEQNLRRFK DRFQQGAKQL KDSEQRWLFA VEVSRYGIWD WNLEDNSVFL SDRWKDMLGY
GPEDLVPELA TWESRLHPED KEGILKNLNA YLNGETEEFE SVHRLRHQQG HYIWVLDRGM
TVEWNEKGKP LRMIGTLSDV TEDIRNQKAA MHQAKHDPLT DLANRRALMD ALYQQQDESG
SCTALFMLDL DNFKVVNDAL GHHGGDRLLI QIAARLSSYF SSNSLIARVA ADEFVVLVKK
LPEDLLGAQR RAQALASQMR QLIARSFHIS GHTFNLSASV GIAIIDPSET IPPEQQLKRV
NMALAQAKES GRDACVVYSS EMDKRAAQNL MIRTELVHAV TRHQLSLFYQ PLLNAKGEIA
SVEALLRWHH PQHGAISPAD FIPVAEGSAL IVELGEWVLL EACRFIRGLQ EQGIRPPMVS
INVSARQFHQ DEFAPKLLVM LKDQGISPAH IELELTEHVL LTDLQQVRQT MTQLREAGVS
IAVDDFGTGY SSLSYLQELP LNRLKLDASF IRDMGNGDAS ASIVKAMIDM SHSLNLEFVA
EGVEIQSQFE QLKAYRCDLY QGYLFHRPMP GEELARLLVR LGDRPLLSSV
//
