ID A3QJH0_SHELP Unreviewed; 416 AA.
AC A3QJH0;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=MscS Mechanosensitive ion channel {ECO:0000313|EMBL:ABO25618.1};
GN OrderedLocusNames=Shew_3752 {ECO:0000313|EMBL:ABO25618.1};
OS Shewanella loihica (strain ATCC BAA-1088 / PV-4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=323850 {ECO:0000313|EMBL:ABO25618.1, ECO:0000313|Proteomes:UP000001558};
RN [1] {ECO:0000313|EMBL:ABO25618.1, ECO:0000313|Proteomes:UP000001558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1088 / PV-4 {ECO:0000313|Proteomes:UP000001558};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Romine M.F., Serres G.,
RA Fredrickson J., Tiedje J., Richardson P.;
RT "Complete sequence of Shewanella loihica PV-4.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP000606; ABO25618.1; -; Genomic_DNA.
DR RefSeq; WP_011867546.1; NC_009092.1.
DR AlphaFoldDB; A3QJH0; -.
DR STRING; 323850.Shew_3752; -.
DR KEGG; slo:Shew_3752; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_045354_1_0_6; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000001558; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0071470; P:cellular response to osmotic stress; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR030192; YbdG.
DR PANTHER; PTHR30414:SF0; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG; 1.
DR PANTHER; PTHR30414; UNCHARACTERIZED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001558};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..258
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 335..399
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 416 AA; 46650 MW; 99399B0B45575EA8 CRC64;
MDQELRAQVS LWLTHFGIDS PSDGVSTGVM VFACLLIAFI GYVVVKRGVV STMNIVIQRS
KVRWDDIFMQ HRVLEKLAKL VPALILNILL PLALVEHPLL SSLADRLLDV AIVILFVRAV
YSVLDAGNEI ADVNQISRRL PIKSFVQLLK LFMFFVAIVI SISVLAEQSP VYFLSGLGVA
TGLVMLVFKD TILGFVAGIQ LAANRMVSPG DWIQMDKYGA DGAVEEVSLT TVKVQNWDKT
ITMIPAYALV SDAFKNWRGM SESGGRRIKR AVNIDIDSIA FLSDEQLKRL GKINLLKEYL
ARKEVEIAEF NAKIQDGDMP VNSRNLTNVG TFRAYLLEYM RKHPKVHQEM TLLVRQLAPT
TEGLPIEIYI FTNDTRWAFY EDIQADIFDH IYAILPQFNL RAFQAPTGAD VRSLKG
//
