ID A3SJ24_ROSNI Unreviewed; 803 AA.
AC A3SJ24;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Aminomethyl transferase family protein {ECO:0000313|EMBL:EAP77355.1};
GN ORFNames=ISM_03660 {ECO:0000313|EMBL:EAP77355.1};
OS Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=89187 {ECO:0000313|EMBL:EAP77355.1, ECO:0000313|Proteomes:UP000005954};
RN [1] {ECO:0000313|EMBL:EAP77355.1, ECO:0000313|Proteomes:UP000005954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-591 / DSM 15170 / ISM
RC {ECO:0000313|Proteomes:UP000005954};
RA Moran M.A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAP77355.1}.
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DR EMBL; AALY01000001; EAP77355.1; -; Genomic_DNA.
DR RefSeq; WP_009812756.1; NZ_CH724156.1.
DR AlphaFoldDB; A3SJ24; -.
DR STRING; 89187.ISM_03660; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_0_5; -.
DR OrthoDB; 9804379at2; -.
DR Proteomes; UP000005954; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005954};
KW Transferase {ECO:0000313|EMBL:EAP77355.1}.
FT DOMAIN 6..368
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 371..424
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 427..694
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 730..795
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 803 AA; 87851 MW; 7ACB77567EB92B73 CRC64;
MQSHAKVVIV GGGMMGVGLA YHLAEEGWKD VLLIEKGELT SGSTWHAAGQ CPSFISNYNM
AKIHHYSNTL YPRLEEITGQ PAGWHGCGGI RLATTQEEVD WFRHVAGFSA NVGFHMEVIG
PERIKELNPW LETDGILAGA YTNMDGHVDP SSACNAMAAG ARQMGATIIR RTRVTDIQVL
PSGEFDVVTD QGTVRAEHVV NAAGCYAREV GKWVGVETPI TNMEHQYLVT EPLAEFAGSD
FELPVMRDPA TAGYYRQEQK AGLVGIYEHY GSREAWAGRG GFPEWDSENE LFEGDIDRIA
PWLEKALERM PIFANAGIKR IINGAIPHTP DGNPLVGPAP GLRNFWQCCG SAIGIAQGAG
TGKYLAQWMV HGDAEINMHC VDPRRFGAYA TPDYTRAKSF DDYENMFETP LPGREVHAGR
PSRVTPLYAP LKSKGAVYTE VYGWERPKYF APDGFEEKLQ YRRNNVFDIV AEECRAVRER
VGVMDLSSFA KFDVSGPGAE ALLDRLTANR LPRKQGGITL THVLSENGRI EGEWTITRLG
DDRFYVLSGA GTERMARDQL SLAAGADVEI SNVTDRYGML VVAGPKSRDV LAPLTDADLS
NAGFRWLSGQ EIEIAGIPVR ALRVNYVGEL GWELHAPMAD LARLYDAIWA SGTDHGIADF
GVQAVNSLRM EKGYRGYAAE LTNEITLIEA DCQRFYAPDK GDFIGRAATE KVHQEGIVTK
LVYGEVAATD CDIYGGEAVM QGDRVVGVCT SGGYGHATGK SLAFAYVSPE ITEGLEVVVL
GERRAFTLHD APVWDPDNAR QKA
//
