ID   A3SNQ9_ROSNI            Unreviewed;       801 AA.
AC   A3SNQ9;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=Dehydrogenase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ISM_14575 {ECO:0000313|EMBL:EAP76099.1};
OS   Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=89187 {ECO:0000313|EMBL:EAP76099.1, ECO:0000313|Proteomes:UP000005954};
RN   [1] {ECO:0000313|EMBL:EAP76099.1, ECO:0000313|Proteomes:UP000005954}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-591 / DSM 15170 / ISM
RC   {ECO:0000313|Proteomes:UP000005954};
RA   Moran M.A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA   Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAP76099.1}.
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DR   EMBL; AALY01000002; EAP76099.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3SNQ9; -.
DR   STRING; 89187.ISM_14575; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_11_1_5; -.
DR   Proteomes; UP000005954; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005954}.
FT   DOMAIN          2..356
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          359..413
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          417..684
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          725..793
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   801 AA;  88760 MW;  5412161F3838899A CRC64;
     MIGGGVIGCS ILYHLTKLGW TDVMLLERDE LTSGSTWHAA ANIHGLHDSA NISRLQHYTM
     TLYNELEAET GQSCGVFQPG SLYLAQTEAR EHQLRLQAAK AKLYGMNFHE VSRDEAERLH
     PLVNFDGIRC IMWEPDGGNV DPSGVTNAYA VGARQRGAEI HRFTPVTGTD QQPDGSWIVR
     TPKGDIHTEW VINAAGLWGR EVAALAGIEV PLQPTEHQYF VTETIAEIDA MDRRLPSVAD
     RDGEYYLRQE GKGLLIGAYE KDMRFWAENG TPLDFAHDLF ADDLDRIMEN VMRAMDRVPV
     AAEAGVKRVI NGPMIWSPDS NVILGPVPEL KNYFMCGGII PGFSQSAGMG LMCAQWMIEG
     EMKYDMFPWD VARFGLWAND RKFVKAKVED VYSHRFAIHY PNEERAAGRP LRTRPAYEMQ
     KDMGAVFGLN YGWEHPQWFA GEKGAKDTNG FTRQNWWEPV GEECRMLRER AGIIDISNFA
     KYRCKGPGAE DWLNSVFANK MPKSVGRSCL TPLISVRGGI AGDATVTRTA EDEFWIVSSG
     MAERYHKRFF DMVPLPEGTT FESHTEAMCG FNVAGPKSRD MLQRLTNASL ATEDFPFMRS
     KVIELGGVEC LALRVSFTGD LGWELHCKTE DQAKLYAALL EAGKEFGAGP VGARALMSMR
     VEKGYGSWSR EYSPEYYPHE VGLAALCKMD KDFLHKAAAE KALAEPEREQ LVLIHVDEAA
     VTASNADATG GEPIFRDGKG IGRVTSGTYG YSVGMSLALG YVKAGTAAPG DAVDVMILGQ
     PHKAVILHEP PFDPEGKRLR A
//