ID A3TTU0_PSEBH Unreviewed; 647 AA.
AC A3TTU0;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:EAQ05067.1};
GN ORFNames=OB2597_07275 {ECO:0000313|EMBL:EAQ05067.1};
OS Pseudooceanicola batsensis (strain ATCC BAA-863 / DSM 15984 / KCTC 12145 /
OS HTCC2597) (Oceanicola batsensis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudooceanicola.
OX NCBI_TaxID=252305 {ECO:0000313|EMBL:EAQ05067.1, ECO:0000313|Proteomes:UP000004318};
RN [1] {ECO:0000313|EMBL:EAQ05067.1, ECO:0000313|Proteomes:UP000004318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-863 / DSM 15984 / KCTC 12145 / HTCC2597
RC {ECO:0000313|Proteomes:UP000004318};
RX PubMed=20418400; DOI=10.1128/JB.00412-10;
RA Thrash J.C., Cho J.C., Vergin K.L., Giovannoni S.J.;
RT "Genome sequences of Oceanicola granulosus HTCC2516(T) and Oceanicola
RT batsensis HTCC2597(TDelta).";
RL J. Bacteriol. 192:3549-3550(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ05067.1}.
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DR EMBL; AAMO01000001; EAQ05067.1; -; Genomic_DNA.
DR RefSeq; WP_009805684.1; NZ_CH724131.1.
DR AlphaFoldDB; A3TTU0; -.
DR STRING; 252305.OB2597_07275; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_1_2_5; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000004318; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004318};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..236
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..602
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 610..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 71286 MW; 4525A375D858A3AC CRC64;
MKRPTKNTAA GQRTMSRRAL ILGGAQVGFM GLLAMRMRYM QVEEADKFRL LAEENRVNIR
LIPPARGEIF DRNGKPIAVN DPAYRITLTR EDAGDVDTIL SRLQSLINLD DEELERVRTE
LKRTQPFLPV TVADQVPWSE VTKIAVNAPA LPGVTPEVGL TRSYPQGSDL AHVVGYVGPV
SDYDLEKIEA PDQLLFIPRF QLGKVGIEAK LEDDLRGQAG ARRVEVNHVG REMRELDRRE
GQQGRDLQLT IDHTLQNYVQ ARLEGESAAA IVMDVRNGDL LAISSAPSFD PNLFVRGISV
SDYRALTENK YRPLAAKAVQ GIYPPGSTFK MVVALAGLEA GVIGPEDTYY CPGHLTVAGR
RFHCWKRVGH GHMNLEGSLR ESCDVYYYEL ALELGIAKIT DMARRLGLGD RIDLPMSAVA
SGLTPTKAWK REARGEEWVI GDTVNSAIGQ GFVLASPLQL AVMTARIATG NAVTPRLIKK
IDGIEQPVNQ GESIGLNENH LRQVRKAMYS VSNNRKGTAY SSRIIAEDLR MAGKTGTSQV
RNITAKERAA GVRSNADLPW ERRDHALFVD FAPYDDPQIA VAVVIEHGGG GSSAAAPVAR
DITLQALYGG EPPLDAYPTK DRNRIREQQK KLREYRPAAQ TQSKSRA
//
