ID A3TV67_PSEBH Unreviewed; 391 AA.
AC A3TV67;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:EAQ04413.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:EAQ04413.1};
GN ORFNames=OB2597_09724 {ECO:0000313|EMBL:EAQ04413.1};
OS Pseudooceanicola batsensis (strain ATCC BAA-863 / DSM 15984 / KCTC 12145 /
OS HTCC2597) (Oceanicola batsensis).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudooceanicola.
OX NCBI_TaxID=252305 {ECO:0000313|EMBL:EAQ04413.1, ECO:0000313|Proteomes:UP000004318};
RN [1] {ECO:0000313|EMBL:EAQ04413.1, ECO:0000313|Proteomes:UP000004318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-863 / DSM 15984 / KCTC 12145 / HTCC2597
RC {ECO:0000313|Proteomes:UP000004318};
RX PubMed=20418400; DOI=10.1128/JB.00412-10;
RA Thrash J.C., Cho J.C., Vergin K.L., Giovannoni S.J.;
RT "Genome sequences of Oceanicola granulosus HTCC2516(T) and Oceanicola
RT batsensis HTCC2597(TDelta).";
RL J. Bacteriol. 192:3549-3550(2010).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ04413.1}.
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DR EMBL; AAMO01000002; EAQ04413.1; -; Genomic_DNA.
DR RefSeq; WP_009806167.1; NZ_CH724131.1.
DR AlphaFoldDB; A3TV67; -.
DR STRING; 252305.OB2597_09724; -.
DR eggNOG; COG0183; Bacteria.
DR HOGENOM; CLU_031026_0_0_5; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000004318; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:EAQ04413.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004318};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:EAQ04413.1}.
FT DOMAIN 4..260
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 347
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 377
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 391 AA; 40908 MW; 44BE5B593AD47846 CRC64;
MTNVVIASAA RTPVGSFLGS FATTPAHDLG ATVLAELVKR AGIEPGEVSE TILGQVLTGG
QGQNPARQAH INAGLPQESA AWGINQVCGS GLRAVALAAQ HIQLGDADIV AAGGQESMSL
SPHVAHLRAG HKMGDVKYID SMIKDGLWDA FNGYHMGQTA ENVAEKWQIS RDQQDEFALA
SQNKAEAAQK AGKFKDEIVP FTVKTRKGET VVEDDEYIRH GATIEGMQKL KPAFTRDGSV
TAANASGIND GAAGALLMSA ENAEKRGITP LARIVSYATA GLDPSIMGVG PIHASRKALE
KAGWKPEDLD LVEANEAFAA QACAVNKDMG WDPEIVNVNG GAIAIGHPIG ASGARVLNTL
LFEMQRRNAR KGLATLCIGG GMGVAMCVER D
//
