ID A3U5L8_CROAH Unreviewed; 927 AA.
AC A3U5L8;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=Metalloprotease, putative {ECO:0000313|EMBL:EAP87535.1};
GN OrderedLocusNames=CA2559_02230 {ECO:0000313|EMBL:EAP87535.1};
OS Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Croceibacter.
OX NCBI_TaxID=216432 {ECO:0000313|EMBL:EAP87535.1, ECO:0000313|Proteomes:UP000002297};
RN [1] {ECO:0000313|EMBL:EAP87535.1, ECO:0000313|Proteomes:UP000002297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-628 / HTCC2559 / KCTC 12090
RC {ECO:0000313|Proteomes:UP000002297};
RX PubMed=20639333; DOI=10.1128/JB.00733-10;
RA Oh H.M., Kang I., Ferriera S., Giovannoni S.J., Cho J.C.;
RT "The complete genome sequence of Croceibacter atlanticus HTCC2559T.";
RL J. Bacteriol. 192:4796-4797(2010).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the peptidase M36 family.
CC {ECO:0000256|ARBA:ARBA00006006}.
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DR EMBL; CP002046; EAP87535.1; -; Genomic_DNA.
DR RefSeq; WP_013186213.1; NC_014230.1.
DR AlphaFoldDB; A3U5L8; -.
DR STRING; 216432.CA2559_02230; -.
DR KEGG; cat:CA2559_02230; -.
DR eggNOG; COG3291; Bacteria.
DR HOGENOM; CLU_007507_0_0_10; -.
DR OrthoDB; 5377264at2; -.
DR Proteomes; UP000002297; Chromosome.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09596; M36; 1.
DR CDD; cd04818; PA_subtilisin_1; 1.
DR Gene3D; 3.10.170.10; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR011096; FTP_domain.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001842; Peptidase_M36.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR InterPro; IPR026444; Secre_tail.
DR NCBIfam; TIGR04183; Por_Secre_tail; 1.
DR NCBIfam; NF038113; T9SSA_dep_M36; 1.
DR PANTHER; PTHR33478; EXTRACELLULAR METALLOPROTEINASE MEP; 1.
DR PANTHER; PTHR33478:SF1; EXTRACELLULAR METALLOPROTEINASE MEP; 1.
DR Pfam; PF07504; FTP; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF02128; Peptidase_M36; 1.
DR Pfam; PF18962; Por_Secre_tail; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR SUPFAM; SSF52025; PA domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EAP87535.1};
KW Metalloprotease {ECO:0000313|EMBL:EAP87535.1};
KW Protease {ECO:0000313|EMBL:EAP87535.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002297};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..927
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002658990"
FT DOMAIN 67..94
FT /note="FTP"
FT /evidence="ECO:0000259|Pfam:PF07504"
FT DOMAIN 509..586
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 854..926
FT /note="Secretion system C-terminal sorting"
FT /evidence="ECO:0000259|Pfam:PF18962"
SQ SEQUENCE 927 AA; 99915 MW; 1522D67BADDBAB5F CRC64;
MKKNYSTQLL TCLLCFVFTL SGIAQDTNSI ISTYISAHKK DLKLSGAITF HTNSIGNLSN
KNYNVAYLQQ TFNGIKVSNA NATVVLKDNK VISFKHTFIN NLETKLTGAA TAPSLTPNQA
GTAALSALGL TDLNHVQLLD FATKEDINAL QLSQETLTAP LFYEKAANGN YVLTYEIIVK
EPTPHWWLSK INVTTGELVS KYDLNISCNF NAPVVTDANP ALNTHTTHKH VLNTNAPSVL
SKKSTTHSNS YTNIQSDGAI YNAFPLRVET PIHGDRELLI NPSLIATQPV DRPIPSPSGW
HDLDGVLQTN TNGNNVAAYE DSDNSNSASS AGSLVDGGAT LLFDFPLDLT QEPDVYQDAT
IVNLFVWNNY VHDVFYAYGF DEDNGNFQEE DYDRFTGFDI PLVTAHNGDG VAAEAQDGSG
LNNANFATPA DGGNPRMQMF LWGASPFGEF LNVYFSGDFD GLYASTRFPF VDIPRAEDPE
VSGSLVVIED DGAAYTGANG GTAGASPDTD DGCTSIVNAA ALNGNIAVIR RGVCTFTTKI
YNAEDAGAIG VIIVNNVEGE GPANGGGEAT EPITIPTISI SFEDGDPMIN ALNNGESITG
RIIDNGPLAD LVMKDGDLDQ GIIAHEYGHG ISTRLVGGRN NSNCLLSLAF EEQMGEGWSD
FFALVMTQKL TDTAEQPRGI GTYVLGQDVL GSGIRPARYS TDFSVNDYTY EDLGNAEITV
PHGIGFIWST IIWDMYWAFI DEYGFDADMY YGTGGNNMAL QLVMDGLKLQ TCGNVGFVDG
RDAILMADEA LYDGANECLI RSVFARRGVG ALAFQGTAIS RMDQVPDFTI SDPLGTDCEA
VLASQDLNKT LFTVYPNPAS HQIHINSNKN SGLANVEVYD VNGRKVISKN IDLVNTATLN
TAKLETGIYV LQINTDNATY TQKVIIQ
//
