ID A3VD90_9RHOB Unreviewed; 1004 AA.
AC A3VD90;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Sarcosine oxidase, alpha subunit family protein {ECO:0000313|EMBL:EAQ13476.1};
GN ORFNames=RB2654_02144 {ECO:0000313|EMBL:EAQ13476.1};
OS Maritimibacter alkaliphilus HTCC2654.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Maritimibacter.
OX NCBI_TaxID=314271 {ECO:0000313|EMBL:EAQ13476.1, ECO:0000313|Proteomes:UP000002931};
RN [1] {ECO:0000313|EMBL:EAQ13476.1, ECO:0000313|Proteomes:UP000002931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2654 {ECO:0000313|EMBL:EAQ13476.1,
RC ECO:0000313|Proteomes:UP000002931};
RX PubMed=20729358; DOI=10.1128/JB.00873-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of Pelagibaca bermudensis HTCC2601T and Maritimibacter
RT alkaliphilus HTCC2654T, the type strains of two marine Roseobacter
RT genera.";
RL J. Bacteriol. 192:5552-5553(2010).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ13476.1}.
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DR EMBL; AAMT01000004; EAQ13476.1; -; Genomic_DNA.
DR RefSeq; WP_008328289.1; NZ_VNHV01000003.1.
DR AlphaFoldDB; A3VD90; -.
DR STRING; 314271.RB2654_02144; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_011963_0_0_5; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000002931; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002931}.
FT DOMAIN 170..425
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 521..603
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 619..882
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 909..996
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
FT REGION 477..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1004 AA; 108290 MW; 9E889124372AC40A CRC64;
MSHRLDGKGR LIDRSKKLRF TFNGKAMTGY AGDTLASALL GSGQSVMGRS FKYHRPRGVV
ASGVEEPNAL MNLGEGGRFE PNQRATTTPL FDGLTATSQN HWPSLEFDIG AVNDLAARFL
PAGFYYKTFM FPRFAWKHLF EPFIRQSAGL GQVPKEPDAD RYEHVYHHTD VLVIGGGVAG
LAAARAAAAG GAKVMVLEQT AHWGGRAPVD GGQIDGLDPE TWVNNAVQEL ETAENVTLRL
GTMGAGVYDH GYVLGYERVA DATPGDDRPR HRLWRIRAKQ IVTATGAIER PLSFPGNDVP
GVMLASAVRD YVVNWGVAPG RRTVIVTNND DAYLTALALK EAKLEVPAII DVRATLVGPL
ADRARKAGIK LMHGKAVVGV KGKKQVTGVM VADLDGKSTP DAIECDAVAM SGGWSPVVHL
WSHCGGKLNW DDAEAMFKPD PARPPLGADG QGFVLTAGNA SGAMGLAEAL ADGHEAGRQA
AKAAGGTLTR KAAPKAPETE RQPLKQVWIM PTSAGPDKRM KMWLDYQNDV KVSDVQLAAR
EGYASVEHTK RYTTLGMATD QGKLSNINGL AVLSDALGQA IPQTGTTTFR PPYTPISMGA
IAGEARGELF QPIRRTPMHS AHDAAGAVWE PVGHWRRPFC FARTGETDME AVNREIVNTR
DNVGMLDAST LGKILVTGPD AGKFLDMLYT NVMSSLPVGK CRYGLMCTEN GFVTDDGVVA
RIGEQTWLCH TTTGGADRIH GHMEDWLQCE WWDWKVYTAN LTEQYAQVAV AGPKARKVLE
ALGGMDVSKE AMPFMTWADG TLAGIPARVY RISFTGELSY EIAVPANRGA ELWAKVAEAG
AAHGIQPYGT EAMHIMRAEK GFVMIGDETD GTVIPQDLNM GWIISKKKTD YLGKRAQERS
HMASPDRWRL VGLETLDGSV IPDGAYAVGE GFNANGQRNM IGRVTSTYYS PTIRKGIAMG
LIQHGPDRMG EVVDFATLDG TGTVIKAKIV ETCFYDKEGA KADV
//
