ID A3WC03_9SPHN Unreviewed; 555 AA.
AC A3WC03;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Metallo-beta-lactamase hydrolase subunit {ECO:0000313|EMBL:EAQ30273.1};
GN ORFNames=NAP1_05835 {ECO:0000313|EMBL:EAQ30273.1};
OS Erythrobacter sp. NAP1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX NCBI_TaxID=237727 {ECO:0000313|EMBL:EAQ30273.1, ECO:0000313|Proteomes:UP000002995};
RN [1] {ECO:0000313|EMBL:EAQ30273.1, ECO:0000313|Proteomes:UP000002995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAP1 {ECO:0000313|EMBL:EAQ30273.1,
RC ECO:0000313|Proteomes:UP000002995};
RX PubMed=21952547; DOI=10.1128/JB.05845-11;
RA Koblizek M., Janouskovec J., Obornik M., Johnson J.H., Ferriera S.,
RA Falkowski P.G.;
RT "Genome Sequence of the Marine Photoheterotrophic Bacterium Erythrobacter
RT sp. Strain NAP1.";
RL J. Bacteriol. 193:5881-5882(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ30273.1}.
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DR EMBL; AAMW01000001; EAQ30273.1; -; Genomic_DNA.
DR AlphaFoldDB; A3WC03; -.
DR STRING; 237727.NAP1_05835; -.
DR eggNOG; COG0595; Bacteria.
DR HOGENOM; CLU_008727_3_3_5; -.
DR Proteomes; UP000002995; Unassembled WGS sequence.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd07714; RNaseJ_MBL-fold; 1.
DR Gene3D; 3.40.50.10710; Metallo-hydrolase/oxidoreductase; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR InterPro; IPR042173; RNase_J_2.
DR PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR PANTHER; PTHR43694:SF1; RIBONUCLEASE J; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EAQ30273.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000002995};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 23..219
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 555 AA; 59774 MW; 5B8FD3F594FFCCFA CRC64;
MKKNYTPEKE LLFLALGGSG EIGMNVNLYG CDGKWLMVDL GMTFSGGEYP GVDLVFADLE
FIEERTKDLL GIVLTHAHED HIGAVPYFAG ELGVPLYATP FTADLVARKL EEAGLLGKVE
LNIIEEDHGQ FDIGPFSVTY LPLAHSIAEG NALLIDTPYG RVFHTGDWKL DEDPIIGEPT
TEAELRAIGE EGVLALVCDS TNVFNPKPSG SEGAVHKGLM EEIALHKGKR VLVTTFASNV
ARLQTLGEVA RETGRQVCVA GRSLDRIIEV AQDNGYLQDF PETVDFDTAM SLPRGEVLIL
ATGGQGEPRA ALARIADDNH PLELVPGDVV LFSSRQIPGN EIAIGKMQNQ LAAKGITMIT
DRQSLIHVSG HPGRPELEAL YDWLKPEVLV PVHGEIRHMA EQARLGKACG ILAGVVQKNG
DVVRLAPGQP GKIAEVLSGR LVLDGDIIAP ADGEAVTTRR RLSFEGLVVA VLARGQVPVV
EPIGLPLDED LPEFIEETQE DILKAIGKLK GRDANDPAAV HEAARLAARR AARRWSGKNP
QVRVIMPGLG SPEVN
//
