ID A3YY93_9SYNE Unreviewed; 337 AA.
AC A3YY93;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=O-methyltransferase, family 2 {ECO:0000313|EMBL:EAQ75075.1};
GN ORFNames=WH5701_08334 {ECO:0000313|EMBL:EAQ75075.1};
OS Synechococcus sp. WH 5701.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=69042 {ECO:0000313|EMBL:EAQ75075.1, ECO:0000313|Proteomes:UP000002935};
RN [1] {ECO:0000313|EMBL:EAQ75075.1, ECO:0000313|Proteomes:UP000002935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH5701 {ECO:0000313|Proteomes:UP000002935};
RA Scanlan D., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ75075.1}.
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DR EMBL; AANO01000005; EAQ75075.1; -; Genomic_DNA.
DR RefSeq; WP_006170410.1; NZ_CH724159.1.
DR AlphaFoldDB; A3YY93; -.
DR eggNOG; COG2345; Bacteria.
DR HOGENOM; CLU_005533_4_0_3; -.
DR OrthoDB; 7418600at2; -.
DR Proteomes; UP000002935; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF327; ACETYLSEROTONIN O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EAQ75075.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002935};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:EAQ75075.1}.
FT DOMAIN 10..90
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 109..318
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 246
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 337 AA; 37180 MW; 9E8B8C1FE9B0E88D CRC64;
MNEQLNPEKI LQTGLAFWAS KTLLSAVEMG LFTELSSGPE SLDKLSGRLG LHPRSARDFL
DALVALGFLT RTGGEYSNTP ETELFLDRNK PSYLGGILEM ANHRLYPFWN NLTEALRTGQ
PQNEAKSGGP ELFEILYADP ARLKEFLAAM SGISHGANMK IAKTFPWKEY RTFVDVGTAQ
GDLAAQIILA NPHLRGEGFD LPEVAPIFEE YIEGLGIKDR LTFVPGSFFT QDIPPADVIL
MGHILHDWDL PTKKMLIRKA FDAVPTGGAL VVYEAIIDDD RSKNAFGLMM SLNMLIETPG
GFDYTGADCV RWMLEAGFTS TWVEELVGPD SMVVGIK
//
