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Database: UniProt
Entry: A3Z3R6_9SYNE
LinkDB: A3Z3R6_9SYNE
Original site: A3Z3R6_9SYNE 
ID   A3Z3R6_9SYNE            Unreviewed;       362 AA.
AC   A3Z3R6;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 56.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=RS9917_05950 {ECO:0000313|EMBL:EAQ70355.1};
OS   Synechococcus sp. RS9917.
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=221360 {ECO:0000313|EMBL:EAQ70355.1, ECO:0000313|Proteomes:UP000005593};
RN   [1] {ECO:0000313|EMBL:EAQ70355.1, ECO:0000313|Proteomes:UP000005593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS9917 {ECO:0000313|EMBL:EAQ70355.1,
RC   ECO:0000313|Proteomes:UP000005593};
RA   Scanlan D., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA   Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA   Venter J.C.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAQ70355.1}.
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DR   EMBL; AANP01000001; EAQ70355.1; -; Genomic_DNA.
DR   RefSeq; WP_007101166.1; NZ_CH724158.1.
DR   STRING; 221360.RS9917_05950; -.
DR   EnsemblBacteria; EAQ70355; EAQ70355; RS9917_05950.
DR   eggNOG; ENOG4105E99; Bacteria.
DR   eggNOG; COG0722; LUCA.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000005593; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005593};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005593};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       43    339       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   362 AA;  38696 MW;  945F96D1AAD30CF1 CRC64;
     MTTTSDLHVV ENRPLVAPAL LHADLRTDAA ATATVAGTRR TIQSILRGDD QRLLVIVGPC
     SVHDVEAARE YACRLAPLRE RHAAELEVVM RVYFEKPRTT VGWKGLINDP HLDGSYDINT
     GLRLARALLL DLARAGMPAA TELLDPVVPQ YIADLISWTA IGARTTESQT HREMASGLSM
     PVGYKNSTDG SVTIAIHAIQ AASRPHHFLG INGQGIASIV STTGNPDGHL VLRGGSRGTN
     YHLDAVQESA AALAAAGLPD RLMVDCSHGN SNKDYRRQGE VLEAVAAQVR QGSDHVMGVM
     LESHLVEGNQ KLNADRTAMT YGQSITDACI SIDTTESLLE QLAAAVAAGR PLALSRQECQ
     LA
//
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