ID A4BAE8_9GAMM Unreviewed; 412 AA.
AC A4BAE8;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=O-acetylhomoserine sulfhydrylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MED297_10351 {ECO:0000313|EMBL:EAR10904.1};
OS Reinekea blandensis MED297.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Reinekea.
OX NCBI_TaxID=314283 {ECO:0000313|EMBL:EAR10904.1, ECO:0000313|Proteomes:UP000005953};
RN [1] {ECO:0000313|EMBL:EAR10904.1, ECO:0000313|Proteomes:UP000005953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED297 {ECO:0000313|EMBL:EAR10904.1,
RC ECO:0000313|Proteomes:UP000005953};
RA Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR10904.1}.
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DR EMBL; AAOE01000002; EAR10904.1; -; Genomic_DNA.
DR RefSeq; WP_008041477.1; NZ_CH724149.1.
DR AlphaFoldDB; A4BAE8; -.
DR STRING; 314283.MED297_10351; -.
DR HOGENOM; CLU_018986_4_0_6; -.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000005953; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000005953}.
FT MOD_RES 207
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 412 AA; 45338 MW; 3D3481F8CA1E063C CRC64;
MTKVKGFTSR IVHHDRLQRF SDGPIHAPIY NSVPYGYETT EGLEAVFQGK NTGHSYARQS
TPTTDALQSM INQAEGGVGT LVFATGMAAL NATFFALLKQ GDHVIASQYL FGNTFSLLTT
LENFGVSVTF ADLTDARNAK AAMQPNTRLV FAETIANPGT QIPDLEALGQ WCREEQLVFI
VDNTLTSPYL FNPSKVGASL VMNSLSKYFS GHGTVLGGAI TDTGHFDWQG YPHIFEGYRT
GDPKKWALTQ IKKKALRDMG GTLSSDAAYQ ISVGAETIAL RMDRACHNAL SLAQMLENHP
KISRVHYPGL ENHPQHHRAR DWFRHNGAIL SFDLAEGYDC ADLLNRIDLV INATHLGDNR
TLALPMASTI FFEMGAQRRA EFGIGERMIR CSVGIEETDD LLEAFQSALD SL
//
