ID A4BD43_9GAMM Unreviewed; 387 AA.
AC A4BD43;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=MED297_05544 {ECO:0000313|EMBL:EAR09787.1};
OS Reinekea blandensis MED297.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Reinekea.
OX NCBI_TaxID=314283 {ECO:0000313|EMBL:EAR09787.1, ECO:0000313|Proteomes:UP000005953};
RN [1] {ECO:0000313|EMBL:EAR09787.1, ECO:0000313|Proteomes:UP000005953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED297 {ECO:0000313|EMBL:EAR09787.1,
RC ECO:0000313|Proteomes:UP000005953};
RA Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR09787.1}.
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DR EMBL; AAOE01000007; EAR09787.1; -; Genomic_DNA.
DR RefSeq; WP_008048243.1; NZ_CH724155.1.
DR AlphaFoldDB; A4BD43; -.
DR STRING; 314283.MED297_05544; -.
DR HOGENOM; CLU_031031_2_1_6; -.
DR OrthoDB; 9778229at2; -.
DR Proteomes; UP000005953; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43021; NA(+)/H(+) ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43021:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005953};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022449}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..369
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 387 AA; 40963 MW; B104778371BBB329 CRC64;
MLNTAEFLLT IGSLLLLGLV TSALAHRTRL PRVTLLLLFG IVIGPQALDL IPPLFTDRFD
LIADLTLLMV GFLLGGKLTR DSLKTSAWPV MVISICAALL TAVLVAAVLW WAGLSFAIAL
LLGCIASATA PAAILDVVAE TNPDSRFSQL LLSIVAVDDL WALILFGMGM SLVSQMTGHG
VDEPFLMAAF EEMIGAVILG VMLGVPSAYA TGRIRPGQPM LTEALGVVCI CGGLALWLGV
SYLIAAMVLG AVIVNLAEHH DYPFHAIEGV ESLFMLIFFV IAGASLDLSS LGSLSLIGLL
YILMRTAGKF AGAWLGCRLS RTDALTRRWL GLALLPQAGV PIGLALVASA AFPEHRQTLL
SVVIASTVLF DLIGPVLTRR SVLRATR
//
