ID A4BIA3_9GAMM Unreviewed; 369 AA.
AC A4BIA3;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Small-conductance mechanosensitive channel {ECO:0000313|EMBL:EAR08110.1};
GN ORFNames=MED297_00440 {ECO:0000313|EMBL:EAR08110.1};
OS Reinekea blandensis MED297.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Reinekea.
OX NCBI_TaxID=314283 {ECO:0000313|EMBL:EAR08110.1, ECO:0000313|Proteomes:UP000005953};
RN [1] {ECO:0000313|EMBL:EAR08110.1, ECO:0000313|Proteomes:UP000005953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED297 {ECO:0000313|EMBL:EAR08110.1,
RC ECO:0000313|Proteomes:UP000005953};
RA Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR08110.1}.
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DR EMBL; AAOE01000025; EAR08110.1; -; Genomic_DNA.
DR RefSeq; WP_008046361.1; NZ_CH724153.1.
DR AlphaFoldDB; A4BIA3; -.
DR STRING; 314283.MED297_00440; -.
DR HOGENOM; CLU_037945_0_0_6; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000005953; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR045042; YnaI-like.
DR PANTHER; PTHR43634:SF2; MECHANOSENSITIVE ION CHANNEL PROTEIN 2, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43634; OW CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005953};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 146..187
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 188..257
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 267..350
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 369 AA; 42047 MW; 1EFE465A00CCB5F7 CRC64;
MDWLTELETF INGFVAQGSE YRWIIQVFLI VLATLIINYF IRKTFDRLEI RANRTVGRFD
NILIETARRP VRVFVWIGGI LMAADVVRNV SNEPIFDLID PIREVSFIVL FAWFAVRFIR
HGESAVQREG VLENPMDATT ASALGKLLRL SVVITTALVV LQTLGFSISA ILAFGGVGGI
AVGFAAKDIL ANFFGGLMIY LDQPFKVGDW IRSPDKEVEG VVENIGWRLS RIRTFDQRPL
YVPNATFANI SVENPSRMRN RRIYEIVGLR YGDADKIEQV VADVKAMLQE HDEIDQDQTM
IVNVNKFNSS SIDFFVYTFT KTVNWIRYHE VKQDIMVKII DIVERNGAEF AFPTQTLHLK
NDEPVEIEG
//
