ID   A4BL79_9GAMM            Unreviewed;       679 AA.
AC   A4BL79;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   ORFNames=NB231_14643 {ECO:0000313|EMBL:EAR23067.1};
OS   Nitrococcus mobilis Nb-231.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Nitrococcus.
OX   NCBI_TaxID=314278 {ECO:0000313|EMBL:EAR23067.1, ECO:0000313|Proteomes:UP000003374};
RN   [1] {ECO:0000313|EMBL:EAR23067.1, ECO:0000313|Proteomes:UP000003374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nb-231 {ECO:0000313|EMBL:EAR23067.1,
RC   ECO:0000313|Proteomes:UP000003374};
RA   Waterbury J., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA   Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAR23067.1}.
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DR   EMBL; AAOF01000001; EAR23067.1; -; Genomic_DNA.
DR   RefSeq; WP_005003937.1; NZ_CH672427.1.
DR   AlphaFoldDB; A4BL79; -.
DR   STRING; 314278.NB231_14643; -.
DR   eggNOG; COG0834; Bacteria.
DR   eggNOG; COG3706; Bacteria.
DR   HOGENOM; CLU_404820_0_0_6; -.
DR   Proteomes; UP000003374; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003374};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        357..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          525..662
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   679 AA;  74795 MW;  FCCD8C3A3BDF8C89 CRC64;
     MNAAIGPQAN QPSLLKAGRT WWRDAMAGAL VAFPLVAVAV LGIVIVTRVE STLRQQVIQS
     LETTLRASHE ALRIWANERQ QQLRHIAGNR ELRALVGSAP DASKRPLHRA APTSLAISAH
     LDKLLSGNGA WHYFIIDTTL RGLTSKEKDA TTARLIARQR PDLMNRLFAG EAVLIPPIKA
     ESKPGTHSTV LRPAMFAATP ITSANGSILA ALMIRIDPLL SFSEVAHVGR IGASGETYFF
     DRETRMLTAS RFTDQLRRIG LIPKDASSIL TVSIRNPGVD LTRGEVPTVP IEQRPPTLMA
     RSAIVQQAAG HSAIGYRDYR GVWVLGAWLW DKPLGIGLAT EIDENEALAA YHTTRDLFMG
     ALALTVIIAG TTLFGLLTLR WKTEQRIRTL AMFPDKNPMP VLRIDNPLTV GYANGPARRF
     LGLIQDADGI LAPPEWRAVV TRIFKDGRHR SLEIEQDGAI YSFVLTPIPE SGIIYAYGQD
     VTQQKWAEGY LRELSIRDSL TGLANRRHFD EFLDQQWRQL MRSNARIALL FIDIDHFKGY
     NDRYGHQAGD ACLKKIAAVI AGAARRAGDL AARYGGEEFV VVLAQVERPY AQDTAETLRR
     AVENLAIPHQ DSKTASYVTV SIGLVCAKPD AALSASRLLE AADKALYRAK SRGRNRVEFA
     TLKPPQVASP QTRKSHKLK
//