ID A4BVD0_9GAMM Unreviewed; 657 AA.
AC A4BVD0;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Probable sodium/hydrogen antiporter {ECO:0000313|EMBL:EAR20315.1};
GN ORFNames=NB231_02945 {ECO:0000313|EMBL:EAR20315.1};
OS Nitrococcus mobilis Nb-231.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Nitrococcus.
OX NCBI_TaxID=314278 {ECO:0000313|EMBL:EAR20315.1, ECO:0000313|Proteomes:UP000003374};
RN [1] {ECO:0000313|EMBL:EAR20315.1, ECO:0000313|Proteomes:UP000003374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nb-231 {ECO:0000313|EMBL:EAR20315.1,
RC ECO:0000313|Proteomes:UP000003374};
RA Waterbury J., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR20315.1}.
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DR EMBL; AAOF01000025; EAR20315.1; -; Genomic_DNA.
DR AlphaFoldDB; A4BVD0; -.
DR STRING; 314278.NB231_02945; -.
DR eggNOG; COG0025; Bacteria.
DR HOGENOM; CLU_005912_10_1_6; -.
DR Proteomes; UP000003374; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003374};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 85..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..543
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 657 AA; 70599 MW; A07F14146546340A CRC64;
MANLLPIRSK LRYFARHAGN RAAGIQTIAS PHRLAGNAVK RMVCRTCKRY GEDAMSGQPS
VLLVGIGVLS VLSQWLAWQV RLPAILFLLA AGLLIGPTAG WLVPDEFFGP LLFPLISLAV
AVILFEGGLT LRLEEIRGLE APVRRLLTVG VLITWCISAV AAWLFVSLSW DLAVLFGAIT
VVTGPTVILP MLRTIRPSAR VASVLRWEGI VIDPIGALLA VLVFDFVASS GGAQALPETL
LSFALIVVIG LLFGVVAGYL WGLILRNYWL ADYLHNIATL VAVFVVATLA NQARAESGLL
AVTVMGIWLG NMRGIPLEGI LNFKESLSLL LISGLFIILA ARIEPERLLE LGWGALLLLL
SLQLIARPLT VTLATLGSPL TWRERVLLSW IAPRGIVAAA VSAVFAMHLA EAGHPQASLL
VPLTFFVILA TVVLQSATAR ALACVLGVVE PPPRGVLIVG ANPIGRALGE ALQALDFPVL
LVDTNWDNLQ VARMQGLPVY YGNPTSEHAE RHLSLAGLGQ MLAVSPRSDL NRLASLHFAK
EFGRNAVFQL PPGEGVLCSA EVRHHHSQDN LLFDPEATYA KLASRLGRGG KIRATQLSKQ
FGWEEYRRAH AELILLLAVD PGGRLHVNQA AKALALQAGW TALSLVAADE RVTKAKA
//
