ID A4BYM5_9FLAO Unreviewed; 380 AA.
AC A4BYM5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=PI23P_06580 {ECO:0000313|EMBL:EAR12268.1};
OS Polaribacter irgensii 23-P.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=313594 {ECO:0000313|EMBL:EAR12268.1, ECO:0000313|Proteomes:UP000003053};
RN [1] {ECO:0000313|EMBL:EAR12268.1, ECO:0000313|Proteomes:UP000003053}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23-P {ECO:0000313|EMBL:EAR12268.1,
RC ECO:0000313|Proteomes:UP000003053};
RA Murray A., Staley J., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR12268.1}.
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DR EMBL; AAOG01000002; EAR12268.1; -; Genomic_DNA.
DR RefSeq; WP_004569936.1; NZ_CH724148.1.
DR AlphaFoldDB; A4BYM5; -.
DR STRING; 313594.PI23P_06580; -.
DR eggNOG; COG0381; Bacteria.
DR HOGENOM; CLU_041674_1_0_10; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000003053; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000003053}.
FT DOMAIN 29..380
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 380 AA; 42787 MW; FB2B5B7B6433C938 CRC64;
MKKIMLVFGT RPEAIKMAPL VKEFQKYPNQ FETIVCVTGQ HREMLDQVLS LFKIVPDYDL
NIMKHGQDLY EITSRVLLGM KEILTKTVPD LVLVHGDTTT STATSLAAFY QRIEVGHIEA
GLRTNDIYSP WPEEMNRQIT GRIANFHFAP TELSKANLLK EGVSESNILV TGNTVIDSLY
YVIDIMNKDK ETATKVGDLI ESAGYTNLEA GKNKKVLITG HRRENFGDGF LNICKAIKEL
SIKYPEVDFI YPMHLNPNVR KPINEVFNDE TPNNVYFIEP LDYLPFVYLL TKSDIVLTDS
GGIQEEAPGL GKPVLVMRNT TERPEALEAG TVKLVGTSTE KIVFQVSKLI ENKAYYNKMS
KAQNPYGDGK ACGRIIKRLK
//
