ID A4C5A5_9GAMM Unreviewed; 675 AA.
AC A4C5A5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=EAL domain protein {ECO:0000313|EMBL:EAR30737.1};
GN ORFNames=PTD2_04171 {ECO:0000313|EMBL:EAR30737.1};
OS Pseudoalteromonas tunicata D2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=87626 {ECO:0000313|EMBL:EAR30737.1, ECO:0000313|Proteomes:UP000006201};
RN [1] {ECO:0000313|EMBL:EAR30737.1, ECO:0000313|Proteomes:UP000006201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D2 {ECO:0000313|EMBL:EAR30737.1,
RC ECO:0000313|Proteomes:UP000006201};
RA Moran M.A., Kjelleberg S., Egan S., Saunders N., Thomas T., Ferriera S.,
RA Johnson J., Kravitz S., Halpern A., Remington K., Beeson K., Tran B.,
RA Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR30737.1}.
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DR EMBL; AAOH01000001; EAR30737.1; -; Genomic_DNA.
DR RefSeq; WP_009837035.1; NZ_AAOH01000001.1.
DR AlphaFoldDB; A4C5A5; -.
DR STRING; 87626.PTD2_04171; -.
DR eggNOG; COG1455; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_024302_1_0_6; -.
DR Proteomes; UP000006201; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR004501; PTS_EIIC_3.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SMART; SM00052; EAL; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..381
FT /note="PTS EIIC type-3"
FT /evidence="ECO:0000259|PROSITE:PS51105"
FT DOMAIN 426..674
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 675 AA; 76276 MW; 9D3445D3CE2FF994 CRC64;
MKAKSLDFTA IFQSWIHSRY LLSLRESFIA LLPYFVSSAL AILLINGAIN FSLTDSDSRI
NQTVEQSAQL ILLLFPLMVT LSVGFHYSKN LGHSGIVGAI LALLSFAVHS HFLVFNQGEI
SLNPTGSSAY AVVIPSLTSA LLHYISIFLP KNSRYLFGVS EFLKEKLLLV LPFSLVFFGL
FFLIPIFDWL GIQIMLVLTP DPTSSVAELM FERMITTHMF WFFGVHGDNM FTMLFEQSFL
EQDIIPGLNA KTFYDTFVLL GGTGCFVGLI LAALALPKYT HERNIAKLSI PFTIFNFCEI
LLFALPVFLN PILLLPFIIA PCINFLLAYL FLSSGWVGFE QAEISWMTPT LINGYQVGTD
LGAIILQLCL ILINTLIYYP FLKWSAEKTN YHLALQRLTE QLHLSEQYAA TSERRFLNQQ
RVSKQSTKAL NSVLNEIAQG QLQLHYQPQV CLLTGKVQGF EALLRLKTAQ GKLIGPYFLD
TLVAHQQTEL IDLWVMEQTA RDLLHWRKQG FVPIVSINLN PNVLTQAELV EKLCQLFTEF
PNQVKVEIVE SSYLNDQALV CEHISKLKTY GIDTVIDDFG TGYSSLFMLA NLPVNQVKLD
RQFLVQAQTD KGKLLYQHVV NIFIQMGYTI VAEGIETEQE LNWIKSLGVQ VAQGWYYAKA
LPAKDIMEFK LNQAQ
//
