ID A4DA44_ASPFU Unreviewed; 602 AA.
AC A4DA44;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Capsule polysaccharide synthase Cps1, putative {ECO:0000313|EMBL:EBA27212.1};
GN ORFNames=AFUA_8G02320 {ECO:0000313|EMBL:EBA27212.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EBA27212.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EBA27212.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EBA27212.1}.
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DR EMBL; AAHF01000014; EBA27212.1; -; Genomic_DNA.
DR RefSeq; XP_001481400.1; XM_001481350.1.
DR AlphaFoldDB; A4DA44; -.
DR EnsemblFungi; EBA27212; EBA27212; AFUA_8G02320.
DR GeneID; 5077275; -.
DR KEGG; afm:AFUA_8G02320; -.
DR VEuPathDB; FungiDB:Afu8g02320; -.
DR eggNOG; ENOG502SICP; Eukaryota.
DR HOGENOM; CLU_019940_2_0_1; -.
DR InParanoid; A4DA44; -.
DR OMA; QITHAMP; -.
DR OrthoDB; 2724691at2759; -.
DR PHI-base; PHI:11512; -.
DR Proteomes; UP000002530; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050501; F:hyaluronan synthase activity; IBA:GO_Central.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0085029; P:extracellular matrix assembly; IBA:GO_Central.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IBA:GO_Central.
DR GO; GO:0030213; P:hyaluronan biosynthetic process; IBA:GO_Central.
DR GO; GO:0043934; P:sporulation; IEA:UniProt.
DR CDD; cd06434; GT2_HAS; 1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR47844:SF1; EXOSTOSIN-LIKE 2; 1.
DR PANTHER; PTHR47844; SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REGION 472..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..500
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 68258 MW; 72746F88955D87B6 CRC64;
MYELLAFITL PWVIAHPRLF MAVAAATTYF MHSTGRTFHN VRANMASQVT GILPEDLRRD
DVLSNRMTVV FLHLFVFRYL RLIVHLISFW LFYHPTPVPK NPALSPSDCT IILPTVDPKN
RDFEECITSC LRNTPGAIII VTVGDQLTKL TKDIIAPYKR IFPNTEISVR TADEANKRRQ
VAHGLRYVKT KITVLLDDHV VWPTERFLPT ILAPFEDPKV GIVGTNKRVR RTDTGFNIRS
FWNMLGALYL ERHNFEIRAT NAIDNGVFVV SGRTSAHRSE ILKDPKFIAE FTNERFFFGL
FGPLNADDDN FITRWDVRHG WKVKIQYCPD AMIETTLGTY PKFLSQCLRW VRTTWRSNSA
SLFTDRTVWY TQPWCVYAVY WTSFVNFALF YDGALAYTLL KSPLGTADNL KYLAAWIFCT
KMVKLTPYFL REPQDLVMLP GYFAFAYFHS LIKLYAGLTF WETNWGGRNL SAVNTQTGGG
PEGDDDDDDD DDDADDSSDD SIDGGVQLPP TPPSSRRRKT AGSSRAGSGG NASGSNRVQS
RASTVDTKTP RKMQTQAMMR ESSSSRSSTS SSTSSKWQRC PGCRKLHSDS GTVCQVRDVW
GR
//
