ID A4F1G9_9RHOB Unreviewed; 816 AA.
AC A4F1G9;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=FAD dependent oxidoreductase/aminomethyl transferase {ECO:0000313|EMBL:EBA14312.1};
GN ORFNames=RSK20926_09684 {ECO:0000313|EMBL:EBA14312.1};
OS Roseobacter sp. SK209-2-6.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseobacter.
OX NCBI_TaxID=388739 {ECO:0000313|EMBL:EBA14312.1, ECO:0000313|Proteomes:UP000005964};
RN [1] {ECO:0000313|EMBL:EBA14312.1, ECO:0000313|Proteomes:UP000005964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK209-2-6 {ECO:0000313|EMBL:EBA14312.1,
RC ECO:0000313|Proteomes:UP000005964};
RA Ward B., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EBA14312.1}.
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DR EMBL; AAYC01000023; EBA14312.1; -; Genomic_DNA.
DR RefSeq; WP_008210036.1; NZ_AAYC01000023.1.
DR AlphaFoldDB; A4F1G9; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000005964; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005964};
KW Transferase {ECO:0000313|EMBL:EBA14312.1}.
FT DOMAIN 9..370
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 373..427
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 431..701
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 726..808
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 816 AA; 89772 MW; 26D84D58BB845165 CRC64;
MSELPNKARV VIIGGGVIGC SVAYHLAKLG WKDVVLLERK QLTSGTTWHA AGLIAQLRAT
ANMTKLAKYS QELYGSLEEE TGVATGFKRC GSITVALTEE RKEEIFRQAA MARAFGVEVE
EISPEEVKAR YEHLNVGDVT GGVWLPKDGQ GDPANIALAL AKGARQRGAL VKERIKVTDI
SKTGRRVTGV DWASDDGKSQ GHIEADMVVN CAGMWGHEVG RMAGVNVPLH ACEHFYIVTE
GITGLTQMPV LRVPDECAYY KEDAGKILLG AFEPNAKPWA MKGIPDSFEF DQLPEDFDHF
EPILEAACNR MPMLAEAGIH TFFNGPESFT PDDAYHLGLA PEMDNFWVAA GFNSIGIQSA
GGAGMALAQW MDEGQKPFDL GDVDISRMQP FQGNKHYLFE RSKETLGLLY ADHFPYRQKA
TARGVRRTPF HHHLLEQGAV MGEIGGWERA NWFANAGQER EYQYSWKRQN WFENSAAEHK
AVRENVGMYD MSSFGKIRVE GPDAEAFLNY ICGANLSVPT GKIVYTQFLN SRGGIEADVT
VTRLSETAYL VVTPAVTRLA DQTWMMRHKG DFNVVITDVT AGEGVLAVMG PNARKLLQKV
SPNDFSNEVN PFGTAQEIEL GMGLARVHRV TYVGELGWEI YVGADMAGHA FETLFEAGQD
MGLKLCGMHM MDSCRIEKGF RHFGHDITCE DNVIDAGLGF AVKTDKEDFI GKAAVLERKE
SGPKNRMLQF KLTDAEPLLF HNEPIIRDGK YVGYLSSGNY GHTLGAAIGM GYVPCEGESA
AEILGSTYEI DVMGTKVKAE ASLKPMYDPK SERVKV
//
