ID A4F6E4_SACEN Unreviewed; 283 AA.
AC A4F6E4;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Helix-turn-helix protein {ECO:0000313|EMBL:PFG93423.1};
DE SubName: Full=Transcriptional regulator, XRE family {ECO:0000313|EMBL:CAL99618.1};
GN OrderedLocusNames=SACE_0268 {ECO:0000313|EMBL:CAL99618.1};
GN ORFNames=A8924_0664 {ECO:0000313|EMBL:PFG93423.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99618.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAL99618.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAL99618.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG93423.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93423.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AM420293; CAL99618.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG93423.1; -; Genomic_DNA.
DR AlphaFoldDB; A4F6E4; -.
DR STRING; 405948.SACE_0268; -.
DR KEGG; sen:SACE_0268; -.
DR eggNOG; COG1396; Bacteria.
DR HOGENOM; CLU_055817_1_0_11; -.
DR OrthoDB; 2991476at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR043917; DUF5753.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR Pfam; PF19054; DUF5753; 1.
DR Pfam; PF13560; HTH_31; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT DOMAIN 18..71
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 283 AA; 31070 MW; 118A85CD18C3CF98 CRC64;
MGGNTGRTPK ARALGAELRE LRQSHGISQR ELARLVTISN ASMSRYETGD RIPTPEDVAS
IVTALGEGGE LREKLIEMAR DAAQPNWLST GAAGGHNELT TLIEFERTAT HIAEVAPMIV
PGLLQTSDYA RAIMADLPAA EMEPFVTLRV GRRDVLTRRR PVDFEAFIAE HVLRMPIGGH
EVMADQLSHL LKFAELPNVS VRVLPTTLQR WSLVLEGAFI LFRFPKAAPI VNLQHYRSSA
FLYDTADVKD YVDAVDALRE AALSPAASAE LIASCVEEME DIE
//
