ID A4F7S6_SACEN Unreviewed; 336 AA.
AC A4F7S6;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Bile acid:sodium symporter {ECO:0000313|EMBL:CAM00100.1};
DE SubName: Full=Sodium/bile acid cotransporter 7 {ECO:0000313|EMBL:PFG93899.1};
GN OrderedLocusNames=SACE_0759 {ECO:0000313|EMBL:CAM00100.1};
GN ORFNames=A8924_1157 {ECO:0000313|EMBL:PFG93899.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00100.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM00100.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM00100.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG93899.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93899.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AM420293; CAM00100.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG93899.1; -; Genomic_DNA.
DR RefSeq; WP_011873155.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4F7S6; -.
DR STRING; 405948.SACE_0759; -.
DR KEGG; sen:SACE_0759; -.
DR eggNOG; COG0385; Bacteria.
DR HOGENOM; CLU_039013_1_0_11; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR016833; Put_Na-Bile_cotransptr.
DR PANTHER; PTHR18640:SF5; SODIUM_BILE ACID COTRANSPORTER 7; 1.
DR PANTHER; PTHR18640; SOLUTE CARRIER FAMILY 10 MEMBER 7; 1.
DR Pfam; PF13593; SBF_like; 1.
DR PIRSF; PIRSF026166; UCP026166; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 336 AA; 35680 MW; A8DAB214E0F2F1BB CRC64;
MGNIPALFAR IRVDPYVLAI LAAAGTAAFL PVHGIAAAGL DRAITVAIAL LFFVYGARLS
AKEALDGARN WRLHLLILGI TFVLFPLFGL LCGLLVPTVL TPELYVGMAF LCALPSTVQS
SITFTSLARG NVAAAICAST FSNVLGVLLA PLLVSMLVTT SGGALSTDAV RDIVLLLLVP
FVLGQLSRRW VGKWVRLHKR GLGLLERGVI LMAVYAAFST GTVSGIWHQL TLSRIGMLLL
VDAALLASVL ALSSLLARSM GFGRADQVPI VFCGSQKSLA TGLPMATVLL AGQGVGLGVL
PLMLYHQMQL ITCAWLARRF AERERTEVPQ PKQLRA
//
