ID   A4F809_SACEN            Unreviewed;       324 AA.
AC   A4F809;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Exopolyphosphatase/guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase {ECO:0000313|EMBL:PFG93980.1};
DE   SubName: Full=Phosphatase, Ppx/GppA family {ECO:0000313|EMBL:CAM00183.1};
GN   OrderedLocusNames=SACE_0843 {ECO:0000313|EMBL:CAM00183.1};
GN   ORFNames=A8924_1241 {ECO:0000313|EMBL:PFG93980.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00183.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAM00183.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAM00183.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93980.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93980.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC       {ECO:0000256|ARBA:ARBA00007125}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM420293; CAM00183.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93980.1; -; Genomic_DNA.
DR   RefSeq; WP_009944215.1; NZ_PDBV01000001.1.
DR   AlphaFoldDB; A4F809; -.
DR   STRING; 405948.SACE_0843; -.
DR   KEGG; sen:SACE_0843; -.
DR   eggNOG; COG0248; Bacteria.
DR   HOGENOM; CLU_025908_1_2_11; -.
DR   OrthoDB; 9793035at2; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN          36..321
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
SQ   SEQUENCE   324 AA;  34358 MW;  B076FEDF66C523E8 CRC64;
     MSRVAAIDCG TNSIRLLVAD VTVSPGPDSD PDGGTRHLRD IHREMRIVRL GQGVDATGRL
     ADEALERTRA ALVDYANIAR RKGVERIRMV ATSATRDASN REEFFAMVRE TLGIDAEVIT
     GDEEARLSFI GAVGDLDPQD GPFVVTDVGG GSTELVVGTW DGVRADITAA YSADIGCVRL
     TERSLHGDPP AEDEVREAVK VARGILDDAF AAVDSSDART WVGVAGTVTT LSAIAQNLPE
     YDPAAIHLSQ ISRNGLERTT EQLLSMTHDE RAGIGSLHAG RVDVIVGGAL VVKVLAEELS
     ERAGIDSITV SEHDILDGIA LSIS
//