ID A4FAW3_SACEN Unreviewed; 346 AA.
AC A4FAW3;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=6-phosphogluconolactonase (Cycloisomerase 2 family) {ECO:0000313|EMBL:PFG94970.1};
DE SubName: Full=Secreted protein {ECO:0000313|EMBL:CAM01188.1};
GN OrderedLocusNames=SACE_1876 {ECO:0000313|EMBL:CAM01188.1};
GN ORFNames=A8924_2275 {ECO:0000313|EMBL:PFG94970.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM01188.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM01188.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM01188.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG94970.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG94970.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cycloisomerase 2 family.
CC {ECO:0000256|ARBA:ARBA00005564}.
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DR EMBL; AM420293; CAM01188.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG94970.1; -; Genomic_DNA.
DR RefSeq; WP_009942650.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FAW3; -.
DR STRING; 405948.SACE_1876; -.
DR KEGG; sen:SACE_1876; -.
DR eggNOG; COG2706; Bacteria.
DR HOGENOM; CLU_038716_3_0_11; -.
DR OrthoDB; 9790815at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011048; Haem_d1_sf.
DR InterPro; IPR019405; Lactonase_7-beta_prop.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR30344; 6-PHOSPHOGLUCONOLACTONASE-RELATED; 1.
DR PANTHER; PTHR30344:SF1; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF10282; Lactonase; 1.
DR SUPFAM; SSF51004; C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:PFG94970.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT REGION 134..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 36052 MW; 9CF47D2E646AA239 CRC64;
MPDNGEYRMY VGAYTADESK ADGIRLAVAD GTGAVRCTDV VHTAADPSFL ALSPDGSTLF
AVSEVWEGRV LSFAVCDDGS LREVNSQPTL GSGPCHLSVH PSGRFLLTAN YVSGNVVVHP
VAEGGVLREP CHVVQHSGSG PSDRQDGPHA HQVLSDPTGK RVLAADLGTD SVYVYDFDAE
SGHLAIRTEV TVAAGAGPRH LAFHPSGTRF YLLNELALAL TEVAYDPETG AAEAGRTLPT
VPDDHREKSL AAEVVVSPDG RFAFASNRGH DSIAVFGCDD FRLLGIHPAG VAGPRHIALS
PDGAVLFAAG QDSGTLRALR VRGDGGLEPV GEPVETPAPV CLLPVA
//
