ID   A4FAX2_SACEN            Unreviewed;       218 AA.
AC   A4FAX2;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAM01197.1};
GN   OrderedLocusNames=SACE_1885 {ECO:0000313|EMBL:CAM01197.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM01197.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAM01197.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the UPF0126 family.
CC       {ECO:0000256|ARBA:ARBA00008193}.
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DR   EMBL; AM420293; CAM01197.1; -; Genomic_DNA.
DR   RefSeq; WP_011873494.1; NZ_PDBV01000001.1.
DR   AlphaFoldDB; A4FAX2; -.
DR   STRING; 405948.SACE_1885; -.
DR   KEGG; sen:SACE_1885; -.
DR   eggNOG; COG2860; Bacteria.
DR   HOGENOM; CLU_064906_1_1_11; -.
DR   OrthoDB; 9791874at2; -.
DR   Proteomes; UP000006728; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR005115; Gly_transporter.
DR   PANTHER; PTHR30506; INNER MEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR30506:SF3; UPF0126 INNER MEMBRANE PROTEIN YADS; 1.
DR   Pfam; PF03458; Gly_transporter; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          13..87
FT                   /note="Glycine transporter"
FT                   /evidence="ECO:0000259|Pfam:PF03458"
FT   DOMAIN          99..173
FT                   /note="Glycine transporter"
FT                   /evidence="ECO:0000259|Pfam:PF03458"
SQ   SEQUENCE   218 AA;  22346 MW;  F30AB1CCBEFB2E05 CRC64;
     MSTVIVSPVV QEILDLIGIF AFGLSGALLA VRKRFDAVGI AVLAEVTALG GGVLRDVVIG
     AVPPVAFTDM GYFVTPLVAA ALTYFWHPRL ARINRFVLIF DAFGLGVFCV AGTIKALNYG
     MHPLPAAALG VMTAIGGGAL RDVLAGEVPA LLHPESEIYA VPALLGSALV AGLAALHLLN
     PVTSGLAALI AVTVRLLALR FGWRAPLARG VGSGDGEG
//