ID A4FK87_SACEN Unreviewed; 262 AA.
AC A4FK87;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=DeoR family transcriptional regulator {ECO:0000313|EMBL:CAM04462.1, ECO:0000313|EMBL:PFG98100.1};
GN OrderedLocusNames=SACE_5221 {ECO:0000313|EMBL:CAM04462.1};
GN ORFNames=A8924_5600 {ECO:0000313|EMBL:PFG98100.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM04462.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM04462.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM04462.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG98100.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG98100.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AM420293; CAM04462.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG98100.1; -; Genomic_DNA.
DR RefSeq; WP_009942396.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FK87; -.
DR STRING; 405948.SACE_5221; -.
DR KEGG; sen:SACE_5221; -.
DR eggNOG; COG1349; Bacteria.
DR HOGENOM; CLU_060699_3_0_11; -.
DR OrthoDB; 7688673at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014036; DeoR_C.
DR InterPro; IPR001034; DeoR_HTH.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30363:SF44; GLUCITOL OPERON REPRESSOR; 1.
DR PANTHER; PTHR30363; HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED; 1.
DR Pfam; PF00455; DeoRC; 1.
DR Pfam; PF08220; HTH_DeoR; 1.
DR PRINTS; PR00037; HTHLACR.
DR SMART; SM01134; DeoRC; 1.
DR SMART; SM00420; HTH_DEOR; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00894; HTH_DEOR_1; 1.
DR PROSITE; PS51000; HTH_DEOR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..66
FT /note="HTH deoR-type"
FT /evidence="ECO:0000259|PROSITE:PS51000"
SQ SEQUENCE 262 AA; 28716 MW; 7799F4A0680BE288 CRC64;
MSSAPKKQSP RLLRQQKIVD HVVSNGFASA AELSNLTGVS LMTVHRDLDD LVTRGLLRKF
HGGVSAQPST VFESSSDFRL HTHTREKEAL AAEGLRMVAP GMSVMIDDST TALALARLLP
DVGPLTVVSN YRQVQEALRE VPDIRLIGLG GEYSRTHDSY VGLPCQEMVS SFSVDIVFLS
TSAMNAQMTY HQEQEIVLVK RAMLESASTR VLMMDASKVG RAALHRFAPV SAFDHVLLAG
EFDPELVEAM REHTDVRQAA LT
//
