ID A4FKU5_SACEN Unreviewed; 688 AA.
AC A4FKU5;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=ABC-2 type transporter {ECO:0000313|EMBL:CAM04670.1};
DE SubName: Full=Putative membrane protein {ECO:0000313|EMBL:PFG98308.1};
GN OrderedLocusNames=SACE_5435 {ECO:0000313|EMBL:CAM04670.1};
GN ORFNames=A8924_5816 {ECO:0000313|EMBL:PFG98308.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM04670.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM04670.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM04670.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG98308.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG98308.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM420293; CAM04670.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG98308.1; -; Genomic_DNA.
DR RefSeq; WP_009947508.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FKU5; -.
DR STRING; 405948.SACE_5435; -.
DR KEGG; sen:SACE_5435; -.
DR eggNOG; COG1511; Bacteria.
DR HOGENOM; CLU_004534_1_1_11; -.
DR OrthoDB; 9811483at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR Gene3D; 3.40.1710.10; abc type-2 transporter like domain; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR017501; Phage_infect_YhgE_C.
DR InterPro; IPR017500; Phage_infect_YhgE_N.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03062; pip_yhgE_Cterm; 1.
DR NCBIfam; TIGR03061; pip_yhgE_Nterm; 1.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 5.
DR PANTHER; PTHR43077:SF5; PHAGE INFECTION PROTEIN; 1.
DR PANTHER; PTHR43077; TRANSPORT PERMEASE YVFS-RELATED; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 563..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 594..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 474..667
FT /note="ABC-2 type transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF12698"
FT REGION 432..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 72137 MW; E4C270DB38E93E4D CRC64;
MTTFRLARTE LRRLTSGKLP KLALLAVTLV PLLYGAMYLY ANWDPYGRLS SVPAAVVIDD
EGAARDDGTR LQAGQDVFDE LLESGTFDWQ RVSETQAQQG VSSGRYTFAL VVPKDFSGAL
LSPGEFEPRQ ARLRLITNDA NNYLVGTIAD KVVSEVRKAV AENAGTEAAE QFLLGFSTVH
DKTVQAADGA GKLADGADRL RDGMGQAKDG TAQLSSGAHQ LLDGHHRLAD GSEQLAEGTG
RLTNGADRLH GGLTQLRQAT AALPEQTAKL ADGADKVADG NEKLADKADV LGGVSQDIVD
NLDQSKARIA DQLRQAGVDQ ATIDRVTAGL DQLNSPVTDA NGKVQDQVGQ LRALADGSRQ
VADGNRKLAD ATPAMTGAIG QLTDGAGRLS DGANQLNDGA VQLRDGEREA LNGTSELTDG
ADRLAGGAQQ LADGSGQLAD GSNTLADELG KGADDIPHPD DPTREATAST IGDPVAVDTH
AQVSASTYGA GLAPFFMGLA LWIGGFVLFL LMRPLSSRAL AAGVAPWRIA LGGWLPAAIV
GLVQAVLLYA VVVFAVGVHP AHAWWTLAFL VLTSFAFTAV VHALNAAFGP KGKFIALIIL
VLQLVTAGGT FPWQTIPEPL HPLHQVLPLS YVVSGLRHLL YGGPGMAAVT NAAGVLLCYL
VAGLLLSTIA AWRQRVWTPA RLKPELSL
//
