ID A4FLD0_SACEN Unreviewed; 437 AA.
AC A4FLD0;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Amino acid transporter, APC family {ECO:0000313|EMBL:CAM04855.1};
GN OrderedLocusNames=SACE_5669 {ECO:0000313|EMBL:CAM04855.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM04855.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM04855.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AM420293; CAM04855.1; -; Genomic_DNA.
DR AlphaFoldDB; A4FLD0; -.
DR STRING; 405948.SACE_5669; -.
DR KEGG; sen:SACE_5669; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_045974_0_0_11; -.
DR Proteomes; UP000006728; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42770:SF7; ARGININE_AGMATINE ANTIPORTER; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 437 AA; 45144 MW; 7326C20891BA4CFC CRC64;
MLTVFGGVLL TLSCVTPASS LFIVVPPLVQ TQGTGVVLTL VLGALVSLGV ACCYSELGTR
FPHAGGEYSI VARVLGRGAG WVTFVMSLTM IVVVPPVIAL GTADYLSAFV GLDPSLTGAA
VMALATATAL LDVRSNALVT GIFLGIEVLA AALVAVFGFA NAERPVSTLV APVVPDAAGG
SAPFTAGVLL TGLTVGIFTF QGFGSAVYLS EELRDPRRSV ARTVICSLLA SVLIIVVPTA
AVVLGAPTEA DLAGADFTAI VESWGGPVLA AFVSLTVAAA ILNAVIVMVL QNARVLYASA
RDRAWPSAVN RALTRLHPRW RSPWVATLAV GLPGAVLAGL ADIEALIGVT GVVVAALYLL
LAVAALRSRR QRAEHGWRMP LWPVPAVVTI AAICLALANQ ETTDLLLTGG VVALAGLYYA
CHLRSRRETH WIISKQS
//
