ID A4FR01_SACEN Unreviewed; 619 AA.
AC A4FR01;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=NHL repeat containing protein {ECO:0000313|EMBL:CAM06476.1};
GN OrderedLocusNames=SACE_7318 {ECO:0000313|EMBL:CAM06476.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM06476.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM06476.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
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DR EMBL; AM420293; CAM06476.1; -; Genomic_DNA.
DR RefSeq; WP_009948371.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FR01; -.
DR STRING; 405948.SACE_7318; -.
DR KEGG; sen:SACE_7318; -.
DR eggNOG; COG0526; Bacteria.
DR HOGENOM; CLU_013730_1_0_11; -.
DR OrthoDB; 9811352at2; -.
DR Proteomes; UP000006728; Chromosome.
DR CDD; cd14951; NHL-2_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR045302; NHL2_NHL_rpt_dom.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01436; NHL; 1.
DR Pfam; PF13905; Thioredoxin_8; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 8..153
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 619 AA; 65496 MW; 115A2F278AD963E3 CRC64;
MSAEQQKRRA RVRAPELVGR RWLNTGGREM SLHDFRGKVL VLDFWTFCCI NCLHVLDELR
PLEEEFADEV VVVGVHSPKF EHEADPDAVA AAVQRYAVHH PVLDDPELTT WQHYAVKAWP
TLVVVDPEGY VVHVAAGEGH VETLRGVVAE LVAEHDAKGT LHRGDGPYVP AETENTTLRF
PAKVLPLDGG TLLVSDSAHH SLVEFTADGE TPVRRIGSGE RGRADGAADE ASFAEPAGLA
LLPEDVAAEV GYDVVVADTV NHLLRGVQLA DGEVVTVAGT GEQWRDGSDA GPALETPLTS
PWDVAWWEPA GGVVIAMAGN HTLGLFDPRA GQVRRFAGTT VEGLRDGDAD EAFFAQTSGL
ADGGDRLWLA DSETSALRWV EAGGDGFAVR TAVGAGLFDF GHADGAADQA LFQHPLGVAV
LPDGSVAVCD TYNGAIRRYD PASDEVSTLA DHVAEPSGAA VVDGELVVVA SASHRLERPV
PPGVAAKLVR GTSQQVKRPD TEVGPGELEL AVVFTPPPGT KLDDRYGPST RLEVSSSPEG
LLVEGAGVGT DLNRRLVLAD DIAHGVLHVV AQAASCDDDP SVEHPACRLT RQDWGVPVRV
AAGGPNRLPL VMGGLDDEA
//
