ID A4G476_HERAR Unreviewed; 375 AA.
AC A4G476;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 2.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=CDP-glucose 4,6-dehydratase {ECO:0000313|EMBL:CAL61313.2};
DE EC=4.2.1.45 {ECO:0000313|EMBL:CAL61313.2};
GN Name=rfbG {ECO:0000313|EMBL:CAL61313.2};
GN OrderedLocusNames=HEAR1134 {ECO:0000313|EMBL:CAL61313.2};
OS Herminiimonas arsenicoxydans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Herminiimonas.
OX NCBI_TaxID=204773 {ECO:0000313|EMBL:CAL61313.2, ECO:0000313|Proteomes:UP000006697};
RN [1] {ECO:0000313|EMBL:CAL61313.2, ECO:0000313|Proteomes:UP000006697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ULPAs1 {ECO:0000313|Proteomes:UP000006697};
RX PubMed=17432936; DOI=10.1371/journal.pgen.0030053;
RA Muller D., Medigue C., Koechler S., Barbe V., Barakat M., Talla E.,
RA Bonnefoy V., Krin E., Arsene-Ploetze F., Carapito C., Chandler M.,
RA Cournoyer B., Cruveiller S., Dossat C., Duval S., Heymann M., Leize E.,
RA Lieutaud A., Lievremont D., Makita Y., Mangenot S., Nitschke W., Ortet P.,
RA Perdrial N., Schoepp B., Siguier N., Simeonova D.D., Rouy Z., Segurens B.,
RA Turlin E., Vallenet D., Van Dorsselaer A., Weiss S., Weissenbach J.,
RA Lett M.C., Danchin A., Bertin P.N.;
RT "A tale of two oxidation states: bacterial colonization of arsenic-rich
RT environments.";
RL PLoS Genet. 3:518-530(2007).
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DR EMBL; CU207211; CAL61313.2; -; Genomic_DNA.
DR AlphaFoldDB; A4G476; -.
DR STRING; 204773.HEAR1134; -.
DR KEGG; har:HEAR1134; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_1_7_4; -.
DR Proteomes; UP000006697; Chromosome.
DR GO; GO:0047733; F:CDP-glucose 4,6-dehydratase activity; IEA:UniProtKB-EC.
DR CDD; cd05252; CDP_GD_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR013445; CDP_4_6_deHydtase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR02622; CDP_4_6_dhtase; 1.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CAL61313.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000006697}.
FT DOMAIN 23..337
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
SQ SEQUENCE 375 AA; 42091 MW; AA9C7D275B4E31F4 CRC64;
MWFLRINILF MTLQNTFHNK IVLITGHTGF KGAWLTAWLK QLGAKVVGIA LDPPTDPAHF
TVAHMADNMT DLRVNICDQA ALEEAILAVQ PDFVFHLAAQ SLVRRSYDNP IETWQTNVMG
TLHVLEALRK LDKSCAAVII TSDKCYDNVE WVWGYRETDA MGGPDPYSAS KGAAELAIRS
HIKSYFPKAT SKVRIAAARA GNVIGGGDWA DDRIVPDCVK AWANNDDVEL RNPHSTRPWQ
HVLEPLSGYL SLAAALSQRP ELHGEPFNFG PPAQQNHSVL ELVNQMALYW DQVRWKDVSQ
SAIGPYESGL LKLNCDKALH HLHWRAVMGF EDTVRMTAEW YRAYYQQPMQ IAAVTGEQLD
AYTKLAKQQG LVWAQ
//
