ID A4HGL7_LEIBR Unreviewed; 614 AA.
AC A4HGL7;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=SANT and BTB domain-containing protein {ECO:0000259|Pfam:PF11822};
GN ORFNames=LBRM_28_1810 {ECO:0000313|EMBL:CAM39711.1};
OS Leishmania braziliensis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania;
OC Leishmania braziliensis species complex.
OX NCBI_TaxID=5660 {ECO:0000313|EMBL:CAM39711.1, ECO:0000313|Proteomes:UP000007258};
RN [1] {ECO:0000313|EMBL:CAM39711.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM39711.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM39711.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM39711.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR799003; CAM39711.1; -; Genomic_DNA.
DR RefSeq; XP_001566211.1; XM_001566161.1.
DR AlphaFoldDB; A4HGL7; -.
DR GeneID; 5417087; -.
DR KEGG; lbz:LBRM_28_1810; -.
DR VEuPathDB; TriTrypDB:LbrM.28.1810; -.
DR VEuPathDB; TriTrypDB:LBRM2903_280024200; -.
DR InParanoid; A4HGL7; -.
DR OMA; GPLRTHM; -.
DR Proteomes; UP000007258; Chromosome 28.
DR InterPro; IPR045902; SANBR-like.
DR InterPro; IPR021777; SANBR_BTB.
DR PANTHER; PTHR20946:SF0; SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION; 1.
DR PANTHER; PTHR20946; UNCHARACTERIZED; 1.
DR Pfam; PF11822; SANBR_BTB; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007258}.
FT DOMAIN 11..116
FT /note="SANT and BTB"
FT /evidence="ECO:0000259|Pfam:PF11822"
FT REGION 555..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 66132 MW; 334EED0B67B15F8E CRC64;
MASSTYSAMA EITVQDPVTH NERTFLCALG PLRTHMRYFE PLIQRQMSET TVWPPSASPS
SSAVALTLRA RCDHVTFQWL VNWMSGKTQE ITKDNVVSIC LSSSFLQMQE LSDNALMYLG
VHLSEIVSSS FDLTNLPTHL VLRLSHMVRD TDLAAALLRL HKEGSVNHQN RALVASLLQH
YACHQLGVAD GAEEPLPTDT EVVTRDSTDG SACASVGLPA THSGELTLSP TCSLRWCRLC
ATLFDEGEVY RLGRTSRLSS PECPGQYMPS RPAGGGAHYA ATAGPTLRVG PRGEVFTTHS
AARHAMPIVL EAPPRLKSGG TSASTTAAEA ASPFTAELER WAWRIIGASR YVGCRRCLHL
VSLLDVSQHR CSELPKKYSS PDNESEDVSY LVRWFDYCAE HHVYEREGGL TPMRYSGPAH
VLAEEVVEVP IFASKPELVP QGAAKAFASA TESRNGARAA GMAGTGGMAE DSAGNFTSAF
MSPYSSDIHL WATMPFYVKE VTSKNVVDID ILNYVERQHR LGIEAQQRRA PAVPNSFAMR
LSISPVVTGT AGGRAVGHLA SSSSSPRPLS SIGGTSCGGS VSHSKGRKKS GARGTRPGLS
SRPSPYGTLS STHC
//
