ID A4HQI1_LEIBR Unreviewed; 165 AA.
AC A4HQI1;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 03-MAY-2023, entry version 58.
DE SubName: Full=Putative ubiquitin fusion degradation protein {ECO:0000313|EMBL:CAM44447.1};
DE Flags: Fragment;
GN ORFNames=LBRM_35_6940 {ECO:0000313|EMBL:CAM44447.1};
OS Leishmania braziliensis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania;
OC Leishmania braziliensis species complex.
OX NCBI_TaxID=5660 {ECO:0000313|EMBL:CAM44447.1, ECO:0000313|Proteomes:UP000007258};
RN [1] {ECO:0000313|EMBL:CAM44447.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM44447.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM44447.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM44447.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
CC -!- SIMILARITY: Belongs to the UFD1 family.
CC {ECO:0000256|ARBA:ARBA00006043}.
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DR EMBL; FR799010; CAM44447.1; -; Genomic_DNA.
DR RefSeq; XP_001569306.1; XM_001569256.1.
DR AlphaFoldDB; A4HQI1; -.
DR STRING; 5660.A4HQI1; -.
DR GeneID; 5420290; -.
DR KEGG; lbz:LBRM_35_6940; -.
DR VEuPathDB; TriTrypDB:LbrM.35.6940; -.
DR VEuPathDB; TriTrypDB:LBRM2903_350081300; -.
DR InParanoid; A4HQI1; -.
DR Proteomes; UP000007258; Chromosome 36.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 3.10.330.10; -; 1.
DR Gene3D; 2.40.40.50; Ubiquitin fusion degradation protein UFD1, N-terminal domain; 1.
DR InterPro; IPR004854; Ufd1-like.
DR InterPro; IPR042299; Ufd1-like_Nn.
DR PANTHER; PTHR12555; UBIQUITIN FUSION DEGRADATON PROTEIN 1; 1.
DR PANTHER; PTHR12555:SF13; UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1; 1.
DR Pfam; PF03152; UFD1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007258};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT NON_TER 165
FT /evidence="ECO:0000313|EMBL:CAM44447.1"
SQ SEQUENCE 165 AA; 18622 MW; E068A33DEF74FDE2 CRC64;
MAALPQSYET RLVAVSASSV NQQRINYGSR VLLPSSVLDD LCRMTMVYPL QFEIITPSKK
RVYAAVLEFN AQAGSVVLPD WMFQHLGLRG TMVVKVQSCS LPPGSLVKLR PHQKALVMFE
NPRNLLELRL AQYPVLTKGT TIVISYVDRE FQLDLVEIID MKQQL
//
