ID A4HZ93_LEIIN Unreviewed; 477 AA.
AC A4HZ93; A0A2K4YTK9; A0A381MJJ8;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Surface antigen-like protein {ECO:0000313|EMBL:CAM67826.1};
GN ORFNames=LINJ_21_1410 {ECO:0000313|EMBL:CAM67826.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM67826.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM67826.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM67826.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM67826.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM67826.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796453; CAM67826.1; -; Genomic_DNA.
DR RefSeq; XP_001465405.1; XM_001465368.1.
DR AlphaFoldDB; A4HZ93; -.
DR SMR; A4HZ93; -.
DR STRING; 5671.A4HZ93; -.
DR GeneID; 5068823; -.
DR KEGG; lif:LINJ_21_1410; -.
DR VEuPathDB; TriTrypDB:LINF_210019800; -.
DR eggNOG; ENOG502S1ZQ; Eukaryota.
DR InParanoid; A4HZ93; -.
DR OMA; TLMIGRN; -.
DR OrthoDB; 130761at2759; -.
DR Proteomes; UP000008153; Chromosome 21.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48053; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR48053:SF173; PROTEIN KINASE; 1.
DR Pfam; PF00560; LRR_1; 3.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000008153};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 477 AA; 51876 MW; EB744056D3A87CE1 CRC64;
MCTHASMALV AAVALVLVLP VSRARPVGMR SMSAYTEAQQ LHTRKFLDGF LQSMPNLHSI
WAGDNFCAWK GVTCLRDGVS ISATNWVQLA VSPGRLPEVS SADFDVSQVF VTSISVRANG
RNLSGTLPAS WGLLRNLRKV RLESNNLSGS LPPEWSGLRS LRELYLSNNN LTGTLPASWG
ESMKSLAILN LNRNALAGTL PPEWGRMRSM QTLVLESNRL SGTLPADWRF MRAASTLMIG
RNDLSGTLPH EWAEMSMMEW MDVHSNRLTG WLPAAWATMT FLNTLLLFDN SFTGTLPAEW
ARLEFLEELR MQDNVLVGTL PASWSAMEFM QVLDISENTL SGTLPVLWSS MQSLDTLSIR
GNQLSGSLPI EWRTLPNIMY LHLEGNALCG CLPLNWTSRY VAVTVDEAVM SVNCAIENAC
NDVNIDSISD KISSSCSSST GPNGAVDGSD ATFSSWDASA SSASNDPLSH STGGASS
//
