ID A4I1A8_LEIIN Unreviewed; 559 AA.
AC A4I1A8; A0A2K4YVW3; A0A381MJK4;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Putative epsin {ECO:0000313|EMBL:CAM68536.1};
GN ORFNames=LINJ_25_0680 {ECO:0000313|EMBL:CAM68536.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM68536.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM68536.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM68536.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM68536.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM68536.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796457; CAM68536.1; -; Genomic_DNA.
DR RefSeq; XP_001466099.1; XM_001466062.1.
DR AlphaFoldDB; A4I1A8; -.
DR SMR; A4I1A8; -.
DR STRING; 5671.A4I1A8; -.
DR GeneID; 5069532; -.
DR KEGG; lif:LINJ_25_0680; -.
DR VEuPathDB; TriTrypDB:LINF_250012000; -.
DR eggNOG; KOG2056; Eukaryota.
DR InParanoid; A4I1A8; -.
DR OMA; NPWGQPQ; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000008153; Chromosome 25.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR CDD; cd03571; ENTH; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR12276:SF45; ENTHOPROTIN-RELATED; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
SQ SEQUENCE 559 AA; 62079 MW; 4C2B8DAB61FC4860 CRC64;
MNFTQQLWSV KEWGRVMATR SEYVTIVHEA TNDEKWGPTG PQMDAVCNAY PRGGPEILNE
LRSRLNNRDK SWRPCYKSLL VIDHLARNVD DRYLPEICAL VPLIRTISTS FYYTNPKGVD
HGVSVRERAK KVADLLSDGL QLREERMVAA QIKEKLSHNA SDGGGPNSGS PYSGAGGYGG
FYSGGYGGSR DRDRHRSYGK GSRQAYDSYR SSPPPATVLS RPRTKEEQER CDMEMALRLQ
RDEERRSGVS AEQLEEMYAT KVRQRQNEAE RQKVTAEDDE RLAMRLQQEE EERARREGVS
LPTLNSDKPS STPVKAPLPN PPATNALEEL FAPPLFSQPA VAAPASSADP FDSFLDSRSG
LAPQQNSWGQ PQQQPSSVQN QWGQPQTAND AWGAPQQWPQ QSVPPLQQPV PPLQQPVPPL
QQQQFHPWGQ SATVSTSNSW GQPQQGPSQQ QRVDNNGSAG SWGQAPPPQL RDPWGQPQQQ
QQPQPQQPPQ SSNSWGKFYQ QPQPGHWGQT SAPPAQLSDT WGQPPASNTA RALDSSNSGG
NLGNMWGALD QFSNQQQHK
//
