ID A4I8M9_LEIIN Unreviewed; 341 AA.
AC A4I8M9; A0A2K4Z3D2; A0A381MRY7;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Putative trans-splicing factor {ECO:0000313|EMBL:CAM71176.1};
GN ORFNames=LINJ_33_0140 {ECO:0000313|EMBL:CAM71176.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM71176.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM71176.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM71176.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM71176.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM71176.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796465; CAM71176.1; -; Genomic_DNA.
DR RefSeq; XP_001468098.1; XM_001468061.1.
DR AlphaFoldDB; A4I8M9; -.
DR SMR; A4I8M9; -.
DR STRING; 5671.A4I8M9; -.
DR GeneID; 5072168; -.
DR KEGG; lif:LINJ_33_0140; -.
DR VEuPathDB; TriTrypDB:LINF_330006400; -.
DR eggNOG; KOG2574; Eukaryota.
DR InParanoid; A4I8M9; -.
DR OMA; LACNRMR; -.
DR OrthoDB; 4493115at2759; -.
DR Proteomes; UP000008153; Chromosome 33.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:InterPro.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR027105; Prp31.
DR PANTHER; PTHR13904; PRE-MRNA SPLICING FACTOR PRP31; 1.
DR PANTHER; PTHR13904:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31; 1.
DR Pfam; PF01798; Nop; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008153};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}.
SQ SEQUENCE 341 AA; 38147 MW; 70431518D05B2717 CRC64;
MDEGFDAHVA TVTLEEIPAY EEHEVTLLSD DDALRYDSVT EVTKLLRSSY LSGMLRRLSD
YEQTTGRGKN CIPSDDPEYQ YVSDCSSLVL RIEVEKSRVH VFLRAQYSIR FPELAMFFSD
SVLYAKVVKI IQNSVDLSSV VGQLDELIPS QLLVVVVACA STTSGRDLSP EELSRVLEAC
EELENLEMAK QTFLEYIQCS MPLICPNLCA FLGTGITSQL FAISGSVAKL SIMDPADLAR
LGSRRSNDSG IAIKTTGFLS NCDLVANLPP QLRPKALRLV SRVTLTLARI DANRRAPTNY
EGVRERRLAC NRMRAWLDPP VLRGAGHNMY ERRGRKRRRT S
//
