ID A4IBI6_LEIIN Unreviewed; 478 AA.
AC A4IBI6; A0A2K4Z6J3; A0A381MV96;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Putative chaperone protein DNAj {ECO:0000313|EMBL:CAM72205.1};
GN ORFNames=LINJ_35_3030 {ECO:0000313|EMBL:CAM72205.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM72205.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM72205.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM72205.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM72205.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM72205.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796467; CAM72205.1; -; Genomic_DNA.
DR RefSeq; XP_001469105.1; XM_001469068.1.
DR AlphaFoldDB; A4IBI6; -.
DR SMR; A4IBI6; -.
DR STRING; 5671.A4IBI6; -.
DR GeneID; 5073197; -.
DR KEGG; lif:LINJ_35_3030; -.
DR VEuPathDB; TriTrypDB:LINF_350035100; -.
DR eggNOG; KOG0712; Eukaryota.
DR InParanoid; A4IBI6; -.
DR OMA; PADMHLH; -.
DR OrthoDB; 154044at2759; -.
DR Proteomes; UP000008153; Chromosome 35.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0030544; F:Hsp70 protein binding; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0009408; P:response to heat; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10747; DnaJ_C; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 2.10.230.10; Heat shock protein DnaJ, cysteine-rich domain; 1.
DR Gene3D; 2.60.260.20; Urease metallochaperone UreE, N-terminal domain; 2.
DR HAMAP; MF_01152; DnaJ; 1.
DR InterPro; IPR012724; DnaJ.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR044713; DNJA1/2-like.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR PANTHER; PTHR43888; DNAJ-LIKE-2, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR43888:SF57; PROTEIN DNAJ, PUTATIVE-RELATED; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF57938; DnaJ/Hsp40 cysteine-rich domain; 1.
DR SUPFAM; SSF49493; HSP40/DnaJ peptide-binding domain; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
SQ SEQUENCE 478 AA; 51033 MW; F06A60F17DBF7103 CRC64;
MLRYLSASTA RRACAWSAGA SLSAAPGAAS TFCSSTTPAR LYSSGNKDYY KMLGVDRNAD
LKEIKKAYRK RALETHPDQG GNKEEFAEVA EAYEVLSNPE KRKVYDQYGS EAATNPSMGG
AGMGGFGAGG RSAEDIFAEF FRGGMGGMGG FGDMFGGGPG GRQGTPTLQP LEVRTRLTLE
DVYKGVTKTM RVNRPQVCAD CTGFGTKSKT EKPKCTQCNG SGHVVQQHRM GPGMVQQTIS
ECPRCRGTGT VAKPEDQCHK CHGKGYRTVS QDVTIEIPAG VPSNVTLVVR GEGGTIPGAP
PADMHLHVEL SPHRVFQRRG NDLIVNKDVT LQEALLGLHM PLKLLDGRTV NVETSADQIL
KPEGVIKVTG EGLPGTSGER GDVYIFTHLK MPNKLSDEQK AHIKKAFGKP EKDADASPGN
TVRARVLRES REQLEEQKRS LWASQESGGY SGGGGGNSRR PAGSTHGSGA QQVECATQ
//
